Cover legend: The rostromedial prefrontal cortex in rabbits potently inhibits acquired eyelid responses until the need for the acquired response is fully confirmed. In this regard, the rostromedial prefrontal cortex seems to act as flip-flop mechanism controlling the expression of reflex and acquired behaviors depending on the environmental circumstances. Photography by J.A. Santos and J.C. López-Ramos; editing by R. Leal-Campanario. For more information, see the article by Leal-Campanario in this issue (pages 4378–4386).