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Articles, Development/Plasticity/Repair

GDNF and Endothelin 3 Regulate Migration of Enteric Neural Crest-Derived Cells via Protein Kinase A and Rac1

Akihiro Goto, Kenta Sumiyama, Yuji Kamioka, Eiji Nakasyo, Keisuke Ito, Mitsuhiro Iwasaki, Hideki Enomoto and Michiyuki Matsuda
Journal of Neuroscience 13 March 2013, 33 (11) 4901-4912; https://doi.org/10.1523/JNEUROSCI.4828-12.2013
Akihiro Goto
1Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, and
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Kenta Sumiyama
3Division of Population Genetics, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan,
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Yuji Kamioka
2Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8315, Japan,
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Eiji Nakasyo
4Life & Industrial Products Development Department 1, R&D Division, Olympus Corporation, Hachioji, Tokyo 192-8507, Japan, and
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Keisuke Ito
5Laboratory for Neuronal Differentiation and Regeneration, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
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Mitsuhiro Iwasaki
5Laboratory for Neuronal Differentiation and Regeneration, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
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Hideki Enomoto
5Laboratory for Neuronal Differentiation and Regeneration, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
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Michiyuki Matsuda
1Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, and
2Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8315, Japan,
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.4828-12.2013
PubMed 
23486961
Published By 
Society for Neuroscience
History 
  • Received October 11, 2012
  • Revision received January 22, 2013
  • Accepted January 25, 2013
  • First published March 13, 2013.
  • Version of record published March 13, 2013.
Copyright & Usage 
Copyright © 2013 the authors 0270-6474/13/334901-12$15.00/0

Author Information

  1. Akihiro Goto1,
  2. Kenta Sumiyama3,
  3. Yuji Kamioka2,
  4. Eiji Nakasyo4,
  5. Keisuke Ito5,
  6. Mitsuhiro Iwasaki5,
  7. Hideki Enomoto5, and
  8. Michiyuki Matsuda1,2
  1. 1Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, and
  2. 2Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8315, Japan,
  3. 3Division of Population Genetics, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan,
  4. 4Life & Industrial Products Development Department 1, R&D Division, Olympus Corporation, Hachioji, Tokyo 192-8507, Japan, and
  5. 5Laboratory for Neuronal Differentiation and Regeneration, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
View Full Text

Author contributions

  1. Author contributions: A.G., H.E., and M.M. designed research; A.G., K.S., Y.K., E.N., and M.I. performed research; K.I. and H.E. contributed unpublished reagents/analytic tools; A.G. analyzed data; A.G., H.E., and M.M. wrote the paper.

Disclosures

    • Received October 11, 2012.
    • Revision received January 22, 2013.
    • Accepted January 25, 2013.
  • This work was supported by a Grant-in-Aid for Scientific Research on the Innovative Area “Fluorescence Live imaging” (No. 22113002), by a Research Program of Innovative Cell Biology “Cell Innovation,” and by an Innovative Techno-Hub for the Integrated Medical Bio-imaging Project of the Special Coordination Funds for Promoting Science and Technology by Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. A.G. was supported by a Grant-in-Aid for Japan Society for the Promotion of Science Fellows by MEXT, Japan. We thank Kyoko Hirano, Yoshie Inaoka, Akiko Sakurai-Katsumata, and Akiko Kawagishi for technical assistance and members of the Matsuda Laboratory for their input.

  • Michiyuki Matsuda received a research fund from Olympus Corporation.

  • Correspondence should be addressed to Michiyuki Matsuda, Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Yoshida-Konoe-Cho, Sakyo-ku, Kyoto 606-8315, Japan. matsuda.michiyuki.2c{at}kyoto-u.ac.jp

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The Journal of Neuroscience: 33 (11)
Journal of Neuroscience
Vol. 33, Issue 11
13 Mar 2013
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GDNF and Endothelin 3 Regulate Migration of Enteric Neural Crest-Derived Cells via Protein Kinase A and Rac1
Akihiro Goto, Kenta Sumiyama, Yuji Kamioka, Eiji Nakasyo, Keisuke Ito, Mitsuhiro Iwasaki, Hideki Enomoto, Michiyuki Matsuda
Journal of Neuroscience 13 March 2013, 33 (11) 4901-4912; DOI: 10.1523/JNEUROSCI.4828-12.2013

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GDNF and Endothelin 3 Regulate Migration of Enteric Neural Crest-Derived Cells via Protein Kinase A and Rac1
Akihiro Goto, Kenta Sumiyama, Yuji Kamioka, Eiji Nakasyo, Keisuke Ito, Mitsuhiro Iwasaki, Hideki Enomoto, Michiyuki Matsuda
Journal of Neuroscience 13 March 2013, 33 (11) 4901-4912; DOI: 10.1523/JNEUROSCI.4828-12.2013
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