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Anatomical Segregation of Visual Selection Mechanisms in Human Parietal Cortex

Paolo Capotosto, Annalisa Tosoni, Sara Spadone, Carlo Sestieri, Mauro Gianni Perrucci, Gian Luca Romani, Stefania Della Penna and Maurizio Corbetta
Journal of Neuroscience 3 April 2013, 33 (14) 6225-6229; https://doi.org/10.1523/JNEUROSCI.4983-12.2013
Paolo Capotosto
1Department of Neuroscience and Imaging and Institute of Advanced Biomedical Technologies, Gabriele D'Annunzio University, I-66110 Chieti, Italy, and
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Annalisa Tosoni
1Department of Neuroscience and Imaging and Institute of Advanced Biomedical Technologies, Gabriele D'Annunzio University, I-66110 Chieti, Italy, and
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Sara Spadone
1Department of Neuroscience and Imaging and Institute of Advanced Biomedical Technologies, Gabriele D'Annunzio University, I-66110 Chieti, Italy, and
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Carlo Sestieri
1Department of Neuroscience and Imaging and Institute of Advanced Biomedical Technologies, Gabriele D'Annunzio University, I-66110 Chieti, Italy, and
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Mauro Gianni Perrucci
1Department of Neuroscience and Imaging and Institute of Advanced Biomedical Technologies, Gabriele D'Annunzio University, I-66110 Chieti, Italy, and
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Gian Luca Romani
1Department of Neuroscience and Imaging and Institute of Advanced Biomedical Technologies, Gabriele D'Annunzio University, I-66110 Chieti, Italy, and
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Stefania Della Penna
1Department of Neuroscience and Imaging and Institute of Advanced Biomedical Technologies, Gabriele D'Annunzio University, I-66110 Chieti, Italy, and
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Maurizio Corbetta
1Department of Neuroscience and Imaging and Institute of Advanced Biomedical Technologies, Gabriele D'Annunzio University, I-66110 Chieti, Italy, and
2Department of Neurology, Radiology, Anatomy, Neurobiology, Washington University School of Medicine, St. Louis, Missouri 63110
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    Figure 1.

    Example of the display sequence in the visual search task.

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    Figure 2.

    A, Left, Voxels showing significantly group-wise different fMRI activation after shift versus stay cues, superimposed over an inflated cortical representation of the PALS atlas, along with the corresponding individual sites of TMS stimulation (black spheres). Right, Voxels showing significantly different fMRI activation after left versus right cues and the corresponding stimulation sites. B, The plots show the time course of the BOLD response extracted from peak regions in right mSPL and right vIPS in the group ANOVA maps, indicated by black circles in A. Activity is modulated according to cue type and location, respectively. C, Group mean ± SE target discrimination accuracy for right mSPL (left) and right vIPS (right) as a function of cue type (shift, stay) and cue location (left, right). D, Left, Group mean ± SE target discrimination accuracy for the two rTMS conditions (right mSPL, right vIPS) as a function of cue type (shift, stay). Right, Group mean ± SE target discrimination accuracy for the two rTMS conditions (right mSPL, right vIPS) as a function of cue location (left, right). Duncan's post hoc tests, *p < 0.05.

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    Table 1.

    Individual coordinates of stimulated sites

    Right mSPLRight vIPS
    xyzxyz
    Subject 11−694814−8720
    Subject 27−564725−8523
    Subject 37−635421−9319
    Subject 410−495417−7929
    Subject 59−724434−8322
    Subject 614−615724−7130
    Subject 712−625922−8813
    Subject 83−575424−8516
    Subject 98−515531−7423
    Subject 102−554129−848
    Subject 119−754822−8212
    Subject 1213−666014−8021
    Subject 131−784116−9021
    Subject 141−564323−9318
    Subject 1515−505424−8111
    Mean7.47−61.3350.6022.67−83.6719.07
    SD4.919.126.425.856.256.27
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The Journal of Neuroscience: 33 (14)
Journal of Neuroscience
Vol. 33, Issue 14
3 Apr 2013
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Anatomical Segregation of Visual Selection Mechanisms in Human Parietal Cortex
Paolo Capotosto, Annalisa Tosoni, Sara Spadone, Carlo Sestieri, Mauro Gianni Perrucci, Gian Luca Romani, Stefania Della Penna, Maurizio Corbetta
Journal of Neuroscience 3 April 2013, 33 (14) 6225-6229; DOI: 10.1523/JNEUROSCI.4983-12.2013

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Anatomical Segregation of Visual Selection Mechanisms in Human Parietal Cortex
Paolo Capotosto, Annalisa Tosoni, Sara Spadone, Carlo Sestieri, Mauro Gianni Perrucci, Gian Luca Romani, Stefania Della Penna, Maurizio Corbetta
Journal of Neuroscience 3 April 2013, 33 (14) 6225-6229; DOI: 10.1523/JNEUROSCI.4983-12.2013
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