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Articles, Development/Plasticity/Repair

Extracellular pH and Neuronal Depolarization Serve as Dynamic Switches to Rapidly Mobilize trkA to the Membrane of Adult Sensory Neurons

Geoffrey E. Bray, Zhengxin Ying, Landon D. Baillie, Ruiling Zhai, Sean J. Mulligan and Valerie M.K. Verge
Journal of Neuroscience 8 May 2013, 33 (19) 8202-8215; https://doi.org/10.1523/JNEUROSCI.4408-12.2013
Geoffrey E. Bray
1Department of Anatomy and Cell Biology,
3Cameco MS Neuroscience Research Center, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5E5
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Zhengxin Ying
1Department of Anatomy and Cell Biology,
3Cameco MS Neuroscience Research Center, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5E5
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Landon D. Baillie
2Department of Physiology, and
3Cameco MS Neuroscience Research Center, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5E5
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Ruiling Zhai
1Department of Anatomy and Cell Biology,
3Cameco MS Neuroscience Research Center, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5E5
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Sean J. Mulligan
2Department of Physiology, and
3Cameco MS Neuroscience Research Center, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5E5
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Valerie M.K. Verge
1Department of Anatomy and Cell Biology,
3Cameco MS Neuroscience Research Center, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5E5
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.4408-12.2013
PubMed 
23658159
Published By 
Society for Neuroscience
History 
  • Received September 13, 2012
  • Revision received March 5, 2013
  • Accepted March 30, 2013
  • First published May 8, 2013.
  • Version of record published May 8, 2013.
Copyright & Usage 
Copyright © 2013 the authors 0270-6474/13/338202-14$15.00/0

Author Information

  1. Geoffrey E. Bray1,3,
  2. Zhengxin Ying1,3,
  3. Landon D. Baillie2,3,
  4. Ruiling Zhai1,3,
  5. Sean J. Mulligan2,3, and
  6. Valerie M.K. Verge1,3
  1. 1Department of Anatomy and Cell Biology,
  2. 2Department of Physiology, and
  3. 3Cameco MS Neuroscience Research Center, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5E5
View Full Text

Author contributions

  1. Author contributions: G.E.B., Z.Y., L.D.B., S.J.M., and V.M.K.V. designed research; G.E.B., Z.Y., L.D.B., R.Z., and V.M.K.V. performed research; G.E.B., Z.Y., L.D.B., R.Z., S.J.M., and V.M.K.V. analyzed data; G.E.B., Z.Y., L.D.B., R.Z., S.J.M., and V.M.K.V. wrote the paper.

Disclosures

    • Received September 13, 2012.
    • Revision received March 5, 2013.
    • Accepted March 30, 2013.
  • This work was supported by a grant from the Canadian Institutes of Health Research (V.M.K.V.) MOP74747. G.E.B. was supported by a University of Saskatchewan Graduate Scholarship and Z.Y. by a University of Saskatchewan/China Doctoral Scholarship. We are indebted to J. Johnston for excellent technical and editorial assistance.

  • Correspondence should be addressed to Valerie M.K. Verge, Cameco MS/Neuroscience Research Center, Saskatoon City Hospital, Room 5800, 701 Queen Street, Saskatoon, Saskatchewan, Canada, S7K 0M7. valerie.verge{at}usask.ca

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Jan 20183323
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Feb 202513326
Mar 20251339
Apr 202592011
May 20251173
Total 20252512033
Total2052335713
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The Journal of Neuroscience: 33 (19)
Journal of Neuroscience
Vol. 33, Issue 19
8 May 2013
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Extracellular pH and Neuronal Depolarization Serve as Dynamic Switches to Rapidly Mobilize trkA to the Membrane of Adult Sensory Neurons
Geoffrey E. Bray, Zhengxin Ying, Landon D. Baillie, Ruiling Zhai, Sean J. Mulligan, Valerie M.K. Verge
Journal of Neuroscience 8 May 2013, 33 (19) 8202-8215; DOI: 10.1523/JNEUROSCI.4408-12.2013

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Extracellular pH and Neuronal Depolarization Serve as Dynamic Switches to Rapidly Mobilize trkA to the Membrane of Adult Sensory Neurons
Geoffrey E. Bray, Zhengxin Ying, Landon D. Baillie, Ruiling Zhai, Sean J. Mulligan, Valerie M.K. Verge
Journal of Neuroscience 8 May 2013, 33 (19) 8202-8215; DOI: 10.1523/JNEUROSCI.4408-12.2013
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