Cover legend: Fluorescence image of cultured hippocampal neurons grown in a microfluidic device. The image depicts the elaborate dendritic arbor of an individual neuron (MAP2), which formed after traversing a 150 μm microgroove. The punctate synapsin immunostaining shows that this dendrite is decorated with presynaptic terminals from axons that also traversed the microgroove. For more information see the article by Swanger et al. (pages 8898–8908).