Article Information
- Received November 1, 2012
- Revision received March 12, 2013
- Accepted March 26, 2013
- First published May 15, 2013.
- Version of record published May 15, 2013.
Author Information
Author contributions
Author contributions: K.B., A.M.G., F.S., D.J.D., and S.H. designed research; K.B., P.P., S.O., C.B., J.D.G., and D.J.D. performed research; J.D.G., F.S., and S.H. contributed unpublished reagents/analytic tools; K.B., P.P., S.O., D.J.D., and S.H. analyzed data; K.B. and S.H. wrote the paper.
↵*P.P. and S.O. contributed equally to this work.
Disclosures
- Received November 1, 2012.
- Revision received March 12, 2013.
- Accepted March 26, 2013.
This work was supported by grants from Agence Nationale pour la Recherche, Maladies Rares (Grant ANR-09-BLAN-0080), Association pour la Recherche sur le Cancer (ARC subvention libre n°3188), Fédération pour la Recherche sur le Cerveau (FRC), CNRS, INSERM, and Institut Curie to S.H.. Fellowship support was provided by Fondation pour la Recherche Médicale (K.B.) and by the French Minister of Research (K.B., S.O.). The mouse mutant line was established at the Mouse Clinical Institute (Strasbourg, France) in the Targeted Mutagenesis and Transgenesis Department with funds from Grant ANR-09-BLAN-0080. P.P. and D.J.D. are assistant professors at Université Paris-Sud 11; A.M.G is professor at Université Paris-Sud 11; F.S. and S.H. are INSERM investigators. We thank the staff from Institut Curie facilities: Animal, Histology, Imaging, and Recombinant Protein and Antibody Platforms for help; S. Anne, R. Hen, and members of the Saudou and Humbert's laboratories for discussions.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Sandrine Humbert, Institut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire- Bat.110, Orsay 91405, France. sandrine.humbert{at}curie.fr
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