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Articles, Cellular/Molecular

FACS Array Profiling Identifies Ecto-5′ Nucleotidase as a Striatopallidal Neuron-Specific Gene Involved in Striatal-Dependent Learning

Sabrina L. Ena, Jean-François De Backer, Serge N. Schiffmann and Alban de Kerchove d'Exaerde
Journal of Neuroscience 15 May 2013, 33 (20) 8794-8809; https://doi.org/10.1523/JNEUROSCI.2989-12.2013
Sabrina L. Ena
Laboratory of Neurophysiology, ULB Neuroscience Institute, Université Libre de Bruxelles, B-1070 Brussels, Belgium
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Jean-François De Backer
Laboratory of Neurophysiology, ULB Neuroscience Institute, Université Libre de Bruxelles, B-1070 Brussels, Belgium
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Serge N. Schiffmann
Laboratory of Neurophysiology, ULB Neuroscience Institute, Université Libre de Bruxelles, B-1070 Brussels, Belgium
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Alban de Kerchove d'Exaerde
Laboratory of Neurophysiology, ULB Neuroscience Institute, Université Libre de Bruxelles, B-1070 Brussels, Belgium
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2989-12.2013
PubMed 
23678122
Published By 
Society for Neuroscience
History 
  • Received June 25, 2012
  • Revision received April 8, 2013
  • Accepted April 10, 2013
  • First published May 15, 2013.
  • Version of record published May 15, 2013.
Copyright & Usage 
Copyright © 2013 the authors 0270-6474/13/338794-16$15.00/0

Author Information

  1. Sabrina L. Ena,
  2. Jean-François De Backer,
  3. Serge N. Schiffmann*, and
  4. Alban de Kerchove d'Exaerde*
  1. Laboratory of Neurophysiology, ULB Neuroscience Institute, Université Libre de Bruxelles, B-1070 Brussels, Belgium
View Full Text

Author contributions

  1. Author contributions: S.L.E., S.N.S., and A.d.K.d'E. designed research; S.L.E., J.-F.D.B., and A.d.K.d'E. performed research; S.L.E., J.-F.D.B., S.N.S., and A.d.K.d'E. analyzed data; S.L.E., S.N.S., and A.d.K.d'E. wrote the paper.

  2. ↵*S.N.S. and A.d.K.d'E. contributed equally to this work.

Disclosures

    • Received June 25, 2012.
    • Revision received April 8, 2013.
    • Accepted April 10, 2013.
  • S.L.E. was supported by a FRIA (Fonds pour la formation à la Recherche dans l'Industrie et dans l'Agriculture) PhD fellowship from the Fund for Scientific Research-Fonds de la Recherche Scientifique (FRS-FNRS) (Belgium) and a Biowin grant from the Walloon Region. A.d.K.d'E. is a Research Associate of the FRS-FNRS (Belgium). This study was supported by the Fondation Médicale Reine Elisabeth (Belgium), FRS-FNRS (Belgium), FER (Fonds d'Encouragement à la Recherche) from Université Libre de Bruxelles, the Interuniversity Attraction Poles program (IUAP–P7/10) from the Belgian State, Federal Office for Scientific Affairs, Action de Recherche Concertée from the FWB (Fédération Wallonie-Bruxelles). We thank Professor Linda Thompson and Professor Corrinne Lobe for providing the NT5e knock-out mice and Z/EG mice, respectively; Professor Oberdan Leo and Georgette Vansanten for the expertise with FACS and the use of their FACS facilities; Dr. Fabrice Heizt for his expertise with lentiviral vectors; Professor Nicholas Dale and Dr. Robert Sims for their help with the adenosine biosensors; Delphine Houtteman, Laetitia Cuvelier, and Souad Laghmari for expert technical assistance; and Professor Michele Zoli for the helpful and critical comments on the manuscript. We would like to acknowledge Professor Jean-Marie Vanderwinden and Dr. Frédéric Bollet-Quivogne from the Light Microscopy Facility, Université Libre de Bruxelles, Brussels, Belgium, for their support with the imaging presented herein.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to either Dr. Alban de Kerchove d'Exaerde or Dr. Serge N. Schiffmann, Laboratory of Neurophysiology, Université Libre de Bruxelles 808, Route de Lennik CP601, B-1070 Brussels, Belgium, adekerch{at}ulb.ac.be or sschiffm{at}ulb.ac.be

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The Journal of Neuroscience: 33 (20)
Journal of Neuroscience
Vol. 33, Issue 20
15 May 2013
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FACS Array Profiling Identifies Ecto-5′ Nucleotidase as a Striatopallidal Neuron-Specific Gene Involved in Striatal-Dependent Learning
Sabrina L. Ena, Jean-François De Backer, Serge N. Schiffmann, Alban de Kerchove d'Exaerde
Journal of Neuroscience 15 May 2013, 33 (20) 8794-8809; DOI: 10.1523/JNEUROSCI.2989-12.2013

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FACS Array Profiling Identifies Ecto-5′ Nucleotidase as a Striatopallidal Neuron-Specific Gene Involved in Striatal-Dependent Learning
Sabrina L. Ena, Jean-François De Backer, Serge N. Schiffmann, Alban de Kerchove d'Exaerde
Journal of Neuroscience 15 May 2013, 33 (20) 8794-8809; DOI: 10.1523/JNEUROSCI.2989-12.2013
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