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Brief Communications

CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing

Manasi Malik, James F. Simpson, Ishita Parikh, Bernard R. Wilfred, David W. Fardo, Peter T. Nelson and Steven Estus
Journal of Neuroscience 14 August 2013, 33 (33) 13320-13325; https://doi.org/10.1523/JNEUROSCI.1224-13.2013
Manasi Malik
1Departments of Physiology,
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James F. Simpson
1Departments of Physiology,
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Ishita Parikh
1Departments of Physiology,
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Bernard R. Wilfred
2Pathology, and
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David W. Fardo
3Biostatistics, Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky 40536
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Peter T. Nelson
2Pathology, and
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Steven Estus
1Departments of Physiology,
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1224-13.2013
PubMed 
23946390
Published By 
Society for Neuroscience
History 
  • Received March 21, 2013
  • Revision received May 31, 2013
  • Accepted June 23, 2013
  • First published August 14, 2013.
  • Version of record published August 14, 2013.
Copyright & Usage 
Copyright © 2013 the authors 0270-6474/13/3313320-06$15.00/0

Author Information

  1. Manasi Malik1,
  2. James F. Simpson1,
  3. Ishita Parikh1,
  4. Bernard R. Wilfred2,
  5. David W. Fardo3,
  6. Peter T. Nelson2, and
  7. Steven Estus1
  1. 1Departments of Physiology,
  2. 2Pathology, and
  3. 3Biostatistics, Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky 40536
View Full Text

Author contributions

  1. Author contributions: M.M., P.T.N., and S.E. designed research; M.M., J.F.S., I.P., and B.R.W. performed research; M.M., J.F.S., D.W.F., P.T.N., and S.E. analyzed data; S.E. wrote the paper.

Disclosures

    • Received March 21, 2013.
    • Revision received May 31, 2013.
    • Accepted June 23, 2013.
  • This work was made possible by National Institutes of Health Grants P01-AGO30128 (SE), P30-AG028383 (D.W.F., P.T.N.), and P20-GM103436 (D.W.F.) and the University of Kentucky Bucks for Brains program (M.M.). The University of Kentucky has filed a provisional patent for CD33 inhibition in Alzheimer's disease that includes M.M., J.F.S., I.P., and S.E.

  • Correspondence should be addressed to Dr. Steven Estus, Sanders-Brown Center on Aging, 800 South Limestone Street, Lexington, KY 40536. steve.estus{at}uky.edu

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Jan 2018138122
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May 20252328
Total 202543519133
Total95666022321
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The Journal of Neuroscience: 33 (33)
Journal of Neuroscience
Vol. 33, Issue 33
14 Aug 2013
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CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing
Manasi Malik, James F. Simpson, Ishita Parikh, Bernard R. Wilfred, David W. Fardo, Peter T. Nelson, Steven Estus
Journal of Neuroscience 14 August 2013, 33 (33) 13320-13325; DOI: 10.1523/JNEUROSCI.1224-13.2013

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CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing
Manasi Malik, James F. Simpson, Ishita Parikh, Bernard R. Wilfred, David W. Fardo, Peter T. Nelson, Steven Estus
Journal of Neuroscience 14 August 2013, 33 (33) 13320-13325; DOI: 10.1523/JNEUROSCI.1224-13.2013
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