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PreviousNext
Articles, Cellular/Molecular

Stochastic Calcium Mechanisms Cause Dendritic Calcium Spike Variability

Haroon Anwar, Iain Hepburn, Hermina Nedelescu, Weiliang Chen and Erik De Schutter
Journal of Neuroscience 2 October 2013, 33 (40) 15848-15867; https://doi.org/10.1523/JNEUROSCI.1722-13.2013
Haroon Anwar
1Theoretical Neurobiology, University of Antwerp, 2610 Wilrijk, Belgium, and
2Computational Neuroscience Unit, Okinawa Institute of Science and Technology, Okinawa 904-0495, Japan
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Iain Hepburn
1Theoretical Neurobiology, University of Antwerp, 2610 Wilrijk, Belgium, and
2Computational Neuroscience Unit, Okinawa Institute of Science and Technology, Okinawa 904-0495, Japan
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Hermina Nedelescu
1Theoretical Neurobiology, University of Antwerp, 2610 Wilrijk, Belgium, and
2Computational Neuroscience Unit, Okinawa Institute of Science and Technology, Okinawa 904-0495, Japan
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Weiliang Chen
2Computational Neuroscience Unit, Okinawa Institute of Science and Technology, Okinawa 904-0495, Japan
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Erik De Schutter
1Theoretical Neurobiology, University of Antwerp, 2610 Wilrijk, Belgium, and
2Computational Neuroscience Unit, Okinawa Institute of Science and Technology, Okinawa 904-0495, Japan
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1722-13.2013
PubMed 
24089492
Published By 
Society for Neuroscience
History 
  • Received April 17, 2013
  • Revision received August 19, 2013
  • Accepted August 22, 2013
  • First published October 2, 2013.
  • Version of record published October 2, 2013.
Copyright & Usage 
Copyright © 2013 the authors 0270-6474/13/3315848-20$15.00/0

Author Information

  1. Haroon Anwar1,2,*,
  2. Iain Hepburn1,2,*,
  3. Hermina Nedelescu1,2,
  4. Weiliang Chen2, and
  5. Erik De Schutter1,2
  1. 1Theoretical Neurobiology, University of Antwerp, 2610 Wilrijk, Belgium, and
  2. 2Computational Neuroscience Unit, Okinawa Institute of Science and Technology, Okinawa 904-0495, Japan
View Full Text

Author contributions

  1. Author contributions: H.A., I.H., and E.D.S. designed research; H.A. and I.H. performed research; H.N. and W.C. contributed unpublished reagents/analytic tools; H.A. and I.H. analyzed data; H.A., I.H., and E.D.S. wrote the paper.

  2. ↵*H.A. and I.H. contributed equally to this work.

Disclosures

    • Received April 17, 2013.
    • Revision received August 19, 2013.
    • Accepted August 22, 2013.
  • This work was supported by Okinawa Institute of Science and Technology Promotion Corporation and Okinawa Institute of Science and Technology School Corporation. CUBIT was used under rights and license from Sandia National Laboratories (License Number 09-N06832). We thank E. Rancz, M. Häusser, C. Roome, and B. Kuhn for providing experimental data and S. Hong for discussions.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Erik De Schutter, Computational Neuroscience Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa 904-0495, Japan. erik{at}oist.jp

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The Journal of Neuroscience: 33 (40)
Journal of Neuroscience
Vol. 33, Issue 40
2 Oct 2013
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Stochastic Calcium Mechanisms Cause Dendritic Calcium Spike Variability
Haroon Anwar, Iain Hepburn, Hermina Nedelescu, Weiliang Chen, Erik De Schutter
Journal of Neuroscience 2 October 2013, 33 (40) 15848-15867; DOI: 10.1523/JNEUROSCI.1722-13.2013

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Stochastic Calcium Mechanisms Cause Dendritic Calcium Spike Variability
Haroon Anwar, Iain Hepburn, Hermina Nedelescu, Weiliang Chen, Erik De Schutter
Journal of Neuroscience 2 October 2013, 33 (40) 15848-15867; DOI: 10.1523/JNEUROSCI.1722-13.2013
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