Article Information
- Received April 1, 2013
- Revision received September 6, 2013
- Accepted September 16, 2013
- First published October 23, 2013.
- Version of record published October 23, 2013.
Author Information
- Agnieszka Z. Burzynska1,2,*,
- Douglas D. Garrett1,3,*,
- Claudia Preuschhof4,
- Irene E. Nagel4,
- Shu-Chen Li1,5,
- Lars Bäckman6,
- Hauke R. Heekeren1,4,7, and
- Ulman Lindenberger1
- 1Center for Lifespan Psychology, Max Planck Institute for Human Development, 14195 Berlin, Germany,
- 2Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, Illinois 61820,
- 3Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom,
- 4Department of Education and Psychology, Freie Universität Berlin, 14195 Berlin, Germany,
- 5Department of Psychology, TU Dresden, 01062 Dresden, Germany,
- 6Aging Research Center, Karolinska Institute, SE-113 30 Stockholm, Sweden, and
- 7Max Planck Institute for Human Cognitive and Brain Sciences, 04103 Leipzig, Germany
Author contributions
Author contributions: A.Z.B., D.D.G., S.-C.L., L.B., H.R.H., and U.L. designed research; A.Z.B., C.P., and I.E.N. performed research; D.D.G. contributed unpublished reagents/analytic tools; A.Z.B. and D.D.G. analyzed data; A.Z.B. and D.D.G. wrote the paper.
↵*A.Z.B. and D.D.G. contributed equally to this work.
Disclosures
- Received April 1, 2013.
- Revision received September 6, 2013.
- Accepted September 16, 2013.
D.D.G and U.L. were partially supported by the Max Planck Society-University College London Initiative for Computational Psychiatry and Ageing Research (ICPAR). L.B. was supported by grants from the Swedish Research Council and Swedish Brain Power, an Alexander von Humboldt Research Award, and by a donation from the af Jochnick Foundation. We thank Janina Marchner, Steffen Wiegert, and Concepcion Padilla for help with data analyses.
The authors declare no competing financial interests.
↵aWithin-age-group analyses revealed a similar direction of correlation between FA-BOLD-based task brain score (BS) and mean n-back accuracy (YA: r = 0.25; OA: r = 0.63) and FA-BOLD-based task BS and mean n-back RT (YA: r = −.21; OA: r = −.50). Although effects within the YA group were weaker, Fisher's r-to-z transformation indicated that the correlation coefficients were not significantly different between the YA and OA groups (one-tailed, p > 0.05).
↵bWe performed additional analyses using hit rate, false alarm rate, A′, and hit minus false alarm rate as measures of n-back performance, taking into account possible response bias and sensitivity. All these measures confirmed our accuracy-based results reported above.
- Correspondence should be addressed to Agnieszka Z. Burzynska, Lifelong Brain and Cognition Lab, Beckman Institute for Advanced Science and Technology, University of Illinois, 405 N Mathews Avenue, Urbana, IL 61820. agaburza{at}illinois.edu
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