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Symposium and Mini-Symposium

Pathological Choice: The Neuroscience of Gambling and Gambling Addiction

Luke Clark, Bruno Averbeck, Doris Payer, Guillaume Sescousse, Catharine A. Winstanley and Gui Xue
Journal of Neuroscience 6 November 2013, 33 (45) 17617-17623; DOI: https://doi.org/10.1523/JNEUROSCI.3231-13.2013
Luke Clark
1Department of Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom,
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Bruno Averbeck
2Laboratory for Neuropsychology, National Institute of Mental Health, Bethesda, Maryland 20892,
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Doris Payer
3Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario M5T 1R8, Canada,
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Guillaume Sescousse
4Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, 6525 HP Nijmegen, The Netherlands,
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Catharine A. Winstanley
5Department of Psychology, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada, and
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Gui Xue
6State Key Laboratory of Cognitive Neuroscience and Learning, and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China 100875
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Abstract

Gambling is pertinent to neuroscience research for at least two reasons. First, gambling is a naturalistic and pervasive example of risky decision making, and thus gambling games can provide a paradigm for the investigation of human choice behavior and “irrationality.” Second, excessive gambling involvement (i.e., pathological gambling) is currently conceptualized as a behavioral addiction, and research on this condition may provide insights into addictive mechanisms in the absence of exogenous drug effects. This article is a summary of topics covered in a Society for Neuroscience minisymposium, focusing on recent advances in understanding the neural basis of gambling behavior, including translational findings in rodents and nonhuman primates, which have begun to delineate neural circuitry and neurochemistry involved.

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The Journal of Neuroscience: 33 (45)
Journal of Neuroscience
Vol. 33, Issue 45
6 Nov 2013
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Pathological Choice: The Neuroscience of Gambling and Gambling Addiction
Luke Clark, Bruno Averbeck, Doris Payer, Guillaume Sescousse, Catharine A. Winstanley, Gui Xue
Journal of Neuroscience 6 November 2013, 33 (45) 17617-17623; DOI: 10.1523/JNEUROSCI.3231-13.2013

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Pathological Choice: The Neuroscience of Gambling and Gambling Addiction
Luke Clark, Bruno Averbeck, Doris Payer, Guillaume Sescousse, Catharine A. Winstanley, Gui Xue
Journal of Neuroscience 6 November 2013, 33 (45) 17617-17623; DOI: 10.1523/JNEUROSCI.3231-13.2013
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