Article Information
- Received June 12, 2013
- Revision received October 11, 2013
- Accepted October 31, 2013
- First published December 4, 2013.
- Version of record published December 4, 2013.
Author Information
- Rana S. Moubarak1,2,3,
- Laura Planells-Ferrer1,2,3,
- Jorge Urresti1,2,3,
- Stéphanie Reix1,2,3,
- Miguel F. Segura1,
- Paulina Carriba1,2,3,
- Fernando Marqués-Fernàndez1,2,3,
- Carme Sole4,
- Nuria Llecha-Cano5,
- Joaquin Lopez-Soriano1,2,3,
- Daniel Sanchis6,
- Victor J. Yuste2, and
- Joan X. Comella1,2,3
- 1Institut de Recerca de l'Hospital Universitari de la Vall d'Hebron (VHIR), 08035 Barcelona, Spain,
- 2Institut de Neurociències, Departament de Bioquímica i Biologia Molecular, Facultat de Medicina, Universitat Autònoma de Barcelona, 08193 Bellaterra Spain,
- 3Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Spain,
- 4Departament de Ciències Experimentals i de la Salut, Cell Signalling Unit, Universitat Pompeu Fabra, 08003 Barcelona, Spain,
- 5Laboratoris Clinics, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain, and
- 6Institut de Recerca Biomèdica de Lleida, Universitat de Lleida, 25198 Lleida, Spain
Author contributions
Author contributions: R.S.M., M.F.S., C.S., and J.X.C. designed research; R.S.M., L.P.-F., J.U., P.C., F.M.-F., C.S., and D.S. performed research; R.S.M., L.P.-F., S.R., and J.L.-S. contributed unpublished reagents/analytic tools; R.S.M., L.P.-F., M.F.S., N.L.-C., V.J.Y., and J.X.C. analyzed data; R.S.M. and J.X.C. wrote the paper.
Disclosures
- Received June 12, 2013.
- Revision received October 11, 2013.
- Accepted October 31, 2013.
This work was funded by the Spanish Government Ministerio de Sanidad y Consumo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, CB06/05/1104 to J.X.C.), Ministerio de Economía y Competitividad (SAF2010–19953 to J.X.C.; SAF2012–31485 to V.J.Y.), Instituto de Salud Carlos III (CP11/00052 to M.F.S.), and the Generalitat de Catalunya (Suport als Grups de Recerca Consolidats 2009SGR346). F.M.-F. and L.P.-F. are supported by postgraduate fellowships from the Spanish Government Ministerio de Educación y Ciencia. J.U. is supported by a postgraduate fellowship from the Generalitat de Catalunya. R.S.M. and V.J.Y. were under the Juan de la Cierva and the Ramon y Cajal programs, respectively, from the Ministerio de Educación y Ciencia (Spain), cofinanced by the European Social Fund. M.F.S. is under the Miguel Servet program from the Instituto de Salud Carlos III and cofinanced by the European Regional Development Fund. We thank Dr. Didier Trono (Geneva, Switzerland) for providing the lentiviral plasmids, Dr. John Silke for providing the XIAP mutants, and Dr. Pascal Meier for helpful discussion.
The authors declare no competing financial interests.
- Correspondence should be addressed to either Dr. Rana S. Moubarak or Dr. Joan X. Comella, Cell Signaling and Apoptosis Group, Fundació Institut de Recerca Vall d'Hebron, Edifici Collserola, Laboratori 203, Passeig Vall d'Hebron 119–129, E-08035 Barcelona, Spain, rana.moubarak{at}vhir.org or joan.comella{at}vhir.org
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