Cover legend: A pair of giant reticulospinal neurons called Mauthner cells, two other paired reticulospinal neurons that are morphological homologs to the Mauthner cells, and a superimposed image of a goldfish exhibiting a C-shaped startle response in response to a sound stimulus. Neki et al. revealed escape circuits composed of the Mauthner cells and their homologous neurons in goldfish hindbrain. See the article by Neki et al. in the February 26 issue of The Journal of Neuroscience (pages 3291–3302).