Article Information
- Received November 27, 2013
- Revision received February 27, 2014
- Accepted March 6, 2014
- First published April 2, 2014.
- Version of record published April 2, 2014.
Author Information
- Kimberly A. Young1,
- Teresa R. Franklin1,
- David C.S. Roberts2,
- Kanchana Jagannathan1,
- Jesse J. Suh1,3,
- Reagan R. Wetherill1,
- Ze Wang1,
- Kyle M. Kampman1,
- Charles P. O'Brien1,3, and
- Anna Rose Childress1,3
- 1Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104,
- 2Department of Physiology and Pharmacology, School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27157, and
- 3Philadelphia VA Medical Center, Philadelphia, Pennsylvania 19104
Author contributions
Author contributions: A.R.C. designed research; K.M.K. and A.R.C. performed research; K.A.Y., K.J., Z.W., and A.R.C. analyzed data; K.A.Y., T.F., D.C.S.R., J.J.S., R.R.W., C.P.O., and A.R.C. wrote the paper.
Disclosures
- Received November 27, 2013.
- Revision received February 27, 2014.
- Accepted March 6, 2014.
The authors declare no competing financial interests.
This work was supported by National Institutes of Health Grants T32 DA029974, R01 DA010241, and P50 DA12756, and the Commonwealth of Pennsylvania CURE Addiction Center of Excellence. We thank the research and clinical staff and nurses at the Center for Studies of Addictions, for their expert assistance throughout the study, the technical staff at the University of Pennsylvania Center for Functional Neuroimaging, and Yin Li, for assistance with image processing. We also thank the National Institute on Drug Abuse for providing the study medication.
- Correspondence should be addressed to Anna Rose Childress, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104. childres{at}mail.med.upenn.edu