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Cover legend: Confocal immunofluorescence image showing localization of the transcriptional coactivator Crtc1 in neurons of the adult mouse hippocampus. Crtc1 (green) localizes in neurites and nuclei of CA3 hippocampal and dentate gyrus neurons (red, NeuN) after adeno-associated viral-Crtc1 infection. Composition by Núria Barba. For more information, see article by Parra-Damas et al. (pages 5776–5787).