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Structural Plasticity within the Barrel Cortex during Initial Phases of Whisker-Dependent Learning

Sandra J. Kuhlman, Daniel H. O'Connor, Kevin Fox and Karel Svoboda
Journal of Neuroscience 23 April 2014, 34 (17) 6078-6083; DOI: https://doi.org/10.1523/JNEUROSCI.4919-12.2014
Sandra J. Kuhlman
1Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147,
2Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, and
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Daniel H. O'Connor
1Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147,
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Kevin Fox
1Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147,
3Cardiff School of Bioscience, Cardiff University, Cardiff CF10 3AX, United Kingdom
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Karel Svoboda
1Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147,
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.4919-12.2014
PubMed 
24760867
Published By 
Society for Neuroscience
History 
  • Received October 19, 2012
  • Revision received March 6, 2014
  • Accepted March 23, 2014
  • First published April 23, 2014.
  • Version of record published April 23, 2014.
Copyright & Usage 
Copyright © 2014 the authors 0270-6474/14/346078-06$15.00/0

Author Information

  1. Sandra J. Kuhlman1,2,*,
  2. Daniel H. O'Connor1,*,
  3. Kevin Fox1,3, and
  4. Karel Svoboda1
  1. 1Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147,
  2. 2Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, and
  3. 3Cardiff School of Bioscience, Cardiff University, Cardiff CF10 3AX, United Kingdom
View Full Text

Author contributions

  1. Author contributions: S.J.K., D.H.O., K.F., and K.S. designed research; S.J.K. performed research; S.J.K. analyzed data; S.J.K., D.H.O., K.F., and K.S. wrote the paper.

Disclosures

    • Received October 19, 2012.
    • Revision received March 6, 2014.
    • Accepted March 23, 2014.
  • ↵*S.J.K. and D.H.O. are first coauthors.

  • We thank Ryan Wyatt and Mark Nicholas for help with analysis; Janelia Farm vivarium staff for assistance in water restriction; Denise O'Connor, Daniel Huber, and Leopoldo Petreanu for help with in utero electroporation; and Joshua Trachtenberg, Zengcai Guo, Mac Hooks, Daniel Huber, and Nuo Li for comments on the manuscript. We acknowledge the support of the HHMI visiting scientists program.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Sandra J. Kuhlman, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213. skuhlman{at}andrew.cmu.edu

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The Journal of Neuroscience: 34 (17)
Journal of Neuroscience
Vol. 34, Issue 17
23 Apr 2014
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Structural Plasticity within the Barrel Cortex during Initial Phases of Whisker-Dependent Learning
Sandra J. Kuhlman, Daniel H. O'Connor, Kevin Fox, Karel Svoboda
Journal of Neuroscience 23 April 2014, 34 (17) 6078-6083; DOI: 10.1523/JNEUROSCI.4919-12.2014

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Structural Plasticity within the Barrel Cortex during Initial Phases of Whisker-Dependent Learning
Sandra J. Kuhlman, Daniel H. O'Connor, Kevin Fox, Karel Svoboda
Journal of Neuroscience 23 April 2014, 34 (17) 6078-6083; DOI: 10.1523/JNEUROSCI.4919-12.2014
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Keywords

  • barrel cortex
  • object localization
  • perceptual learning
  • plasticity

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