Articles, Systems/Circuits

Optogenetic Stimulation of Locus Ceruleus Neurons Augments Inhibitory Transmission to Parasympathetic Cardiac Vagal Neurons via Activation of Brainstem α1 and β1 Receptors

Xin Wang, Ramón A. Piñol, Peter Byrne and David Mendelowitz
Journal of Neuroscience 30 April 2014, 34 (18) 6182-6189; https://doi.org/10.1523/JNEUROSCI.5093-13.2014

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.5093-13.2014
PubMed 
24790189
Published By 
Society for Neuroscience
History 
  • Received December 5, 2013
  • Revision received March 21, 2014
  • Accepted March 24, 2014
  • First published April 30, 2014.
  • Version of record published April 30, 2014.
Copyright & Usage 
Copyright © 2014 the authors 0270-6474/14/346182-08$15.00/0

Author Information

  1. Xin Wang,
  2. Ramón A. Piñol,
  3. Peter Byrne, and
  4. David Mendelowitz
  1. Department of Pharmacology and Physiology, Department of Anesthesiology and Critical Care Medicine, The George Washington University, Washington, District of Columbia 20037
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Author contributions

  1. Author contributions: X.W., R.A.P., and D.M. designed research; X.W. and P.B. performed research; X.W. analyzed data; X.W., R.A.P., and D.M. wrote the paper.

View Abstract

Disclosures

    • Received December 5, 2013.
    • Revision received March 21, 2014.
    • Accepted March 24, 2014.

  • This work was supported by the National Institutes of Health (Grants HL49965, HL59895, and HL72006 to D.M.).

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to David Mendelowitz, Department of Pharmacology and Physiology, Department of Anesthesiology and Critical Care Medicine, The George Washington University, 2300 Eye Street, NW, Washington, DC 20037. dmendel{at}gwu.edu

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Apr 202194421
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May 2025104016
Jun 202511103
Total 20257025098
Total69935541171
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Optogenetic Stimulation of Locus Ceruleus Neurons Augments Inhibitory Transmission to Parasympathetic Cardiac Vagal Neurons via Activation of Brainstem α1 and β1 Receptors
Xin Wang, Ramón A. Piñol, Peter Byrne, David Mendelowitz
Journal of Neuroscience 30 April 2014, 34 (18) 6182-6189; DOI: 10.1523/JNEUROSCI.5093-13.2014
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