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Brief Communications

Differential Effects of Presynaptic versus Postsynaptic Adenosine A2A Receptor Blockade on Δ9-Tetrahydrocannabinol (THC) Self-Administration in Squirrel Monkeys

Zuzana Justinová, Godfrey H. Redhi, Steven R. Goldberg and Sergi Ferré
Journal of Neuroscience 7 May 2014, 34 (19) 6480-6484; https://doi.org/10.1523/JNEUROSCI.5073-13.2014
Zuzana Justinová
1Preclinical Pharmacology Section of Behavioral Neuroscience Research Branch and
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Godfrey H. Redhi
1Preclinical Pharmacology Section of Behavioral Neuroscience Research Branch and
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Steven R. Goldberg
1Preclinical Pharmacology Section of Behavioral Neuroscience Research Branch and
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Sergi Ferré
2Integrative Neurobiology Section of Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.5073-13.2014
PubMed 
24806674
Published By 
Society for Neuroscience
History 
  • Received December 4, 2013
  • Revision received March 7, 2014
  • Accepted March 29, 2014
  • First published May 7, 2014.
  • Version of record published May 7, 2014.
Copyright & Usage 
Copyright © 2014 the authors 0270-6474/14/346480-05$15.00/0

Author Information

  1. Zuzana Justinová1,
  2. Godfrey H. Redhi1,
  3. Steven R. Goldberg1, and
  4. Sergi Ferré2
  1. 1Preclinical Pharmacology Section of Behavioral Neuroscience Research Branch and
  2. 2Integrative Neurobiology Section of Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224
View Full Text

Author contributions

  1. Author contributions: Z.J., S.R.G., and S.F. designed research; Z.J. and G.H.R. performed research; Z.J. analyzed data; Z.J., S.R.G., and S.F. wrote the paper.

Disclosures

    • Received December 4, 2013.
    • Revision received March 7, 2014.
    • Accepted March 29, 2014.
  • This work was supported by the Intramural Research Program of the National Institute on Drug Abuse (NIDA), National Institutes of Health, Department of Health and Human Services. THC was provided by the NIDA Drug Supply Program. We thank Dr. Leigh V. Panlilio for his excellent assistance with statistical analysis.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Sergi Ferré, Integrative Neurobiology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 333 Cassell Drive, Baltimore, MD 21224. sferre{at}mail.nih.gov

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The Journal of Neuroscience: 34 (19)
Journal of Neuroscience
Vol. 34, Issue 19
7 May 2014
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Differential Effects of Presynaptic versus Postsynaptic Adenosine A2A Receptor Blockade on Δ9-Tetrahydrocannabinol (THC) Self-Administration in Squirrel Monkeys
Zuzana Justinová, Godfrey H. Redhi, Steven R. Goldberg, Sergi Ferré
Journal of Neuroscience 7 May 2014, 34 (19) 6480-6484; DOI: 10.1523/JNEUROSCI.5073-13.2014

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Differential Effects of Presynaptic versus Postsynaptic Adenosine A2A Receptor Blockade on Δ9-Tetrahydrocannabinol (THC) Self-Administration in Squirrel Monkeys
Zuzana Justinová, Godfrey H. Redhi, Steven R. Goldberg, Sergi Ferré
Journal of Neuroscience 7 May 2014, 34 (19) 6480-6484; DOI: 10.1523/JNEUROSCI.5073-13.2014
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Keywords

  • adenosine A2A receptor
  • cannabinoids
  • drug abuse
  • monkey
  • self-administration
  • THC

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