Cover legend: Confocal micrograph of cultured hippocampal neurons stained for neuronal nitric oxide synthase (nNOS, grey-blue) and the postsynaptic protein gephyrin (red). nNOS activity modulates the clustering of gephyrin at GABAergic synapses. For more information, see the article by Dejanovic and Schwarz (pages 7763–7768). Image edited by Sita Arjune.