Article Information
- Received October 10, 2013
- Revision received April 16, 2014
- Accepted April 18, 2014
- First published June 11, 2014.
- Version of record published June 11, 2014.
Author Information
- Douglas A. Meyer1,
- Melissa I. Torres-Altoro1,
- Zhenjun Tan3,
- Alessandro Tozzi5,6,
- Massimiliano Di Filippo5,6,
- Vincent DiNapoli3,
- Florian Plattner1,
- Janice W. Kansy1,
- Stanley A. Benkovic4,
- Jason D. Huber7,
- Diane B. Miller4,
- Paul Greengard8,
- Paolo Calabresi5,6,
- Charles L. Rosen3, and
- James A. Bibb1,2
- 1Department of Psychiatry,
- 2Department of Neurology and Neurotherapeutics, The University of Texas Southwestern Medical Center, Dallas, Texas 75390,
- 3Department of Neurosurgery, West Virginia University School of Medicine, Morgantown, West Virginia 26506-9183,
- 4National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia 26505,
- 5Clinica Neurologica, Università di Perugia, Ospedale S. Maria della Misericordia, 06156 Perugia, Italy,
- 6Fondazione Santa Lucia-Istituto di Ricovero e Cura a Carattere Scientifico, 00184 Rome, Italy,
- 7Department of Basic Pharmaceutical Sciences, West Virginia University School of Medicine, Morgantown, West Virginia 26506-9530,
- 8Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021
Author contributions
Author contributions: D.B.M., P.C., C.L.R., and J.A.B. designed research; D.A.M., M.I.T.-A., Z.T., A.T., M.D.F., V.D., J.W.K., S.A.B., and J.A.B. performed research; J.A.B. contributed unpublished reagents/analytic tools; D.A.M., M.I.T.-A., Z.T., A.T., M.D.F., P.C., C.L.R., and J.A.B. analyzed data; M.I.T.-A., F.P., J.D.H., D.B.M., P.G., P.C., C.L.R., and J.A.B. wrote the paper.
Disclosures
- Received October 10, 2013.
- Revision received April 16, 2014.
- Accepted April 18, 2014.
This work was supported by the European Community contract number 222918 (REPLACES) FP7—Thematic priority HEALTH to P.C., and U.S. National Institutes of Health grants to P.G. (MH090963 and DA10044), J.D.H. (NS061954), and J.A.B. (MH79710, MH083711, DA016672, DA033485, NS073855). This work was also supported by DA0018343 Pilot Project funding (J.A.B.). We thank W. Lai, X. Li, and M. Kouser, for technical assistance, and F. Gillardon and Boehringer Ingelheim, for indolinone. We thank P. Chambon and Universaire de Srasbourg, for Prp-ERT transgenic mice, and A. Sonneborn, for help with manuscript preparation.
The authors declare no competing financial interests.
- Correspondence should be addressed to James A. Bibb, PhD, at the above address. james.bibb{at}utsouthwestern.edu
Online Impact
