Article Information
- Received April 19, 2014
- Revision received June 9, 2014
- Accepted June 17, 2014
- First published July 30, 2014.
- Version of record published July 30, 2014.
Author Information
- Yvonne S. Eisele1,3,*,
- Sarah K. Fritschi1,2,3,*,
- Tsuyoshi Hamaguchi1,*,
- Ulrike Obermüller1,3,
- Petra Füger1,3,
- Angelos Skodras1,3,
- Claudia Schäfer1,3,
- Jörg Odenthal1,3,
- Mathias Heikenwalder4,
- Matthias Staufenbiel1,3, and
- Mathias Jucker1,3
- 1Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, D-72076 Tübingen, Germany,
- 2Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, D-72074 Tübingen, Germany,
- 3German Center for Neurodegenerative Diseases, D-72076 Tübingen, Germany, and
- 4Institute for Virology, Technische Universität München/Helmholtz Zentrum München, D-81675 Munich, Germany
Author contributions
Author contributions: Y.S.E., S.K.F., T.H., M.S., and M.J. designed research; Y.S.E., S.K.F., T.H., U.O., and C.S. performed research; J.O. and M.H. contributed unpublished reagents/analytic tools; Y.S.E., S.K.F., T.H., P.F., A.S., and M.J. analyzed data; Y.S.E., S.K.F., M.S., and M.J. wrote the paper.
↵*Y.S.E., S.K.F., and T.H. contributed equally to this work.
Disclosures
- Received April 19, 2014.
- Revision received June 9, 2014.
- Accepted June 17, 2014.
This work was supported by grants from the Competence Network on Degenerative Dementias (BMBF-01GI0705) and the BMBF as part of ERA-Net NEURON (MIPROTRAN). T.H. was supported by a postdoctoral fellowship from the Humboldt foundation. We thank Lary Walker (Atlanta, GA) and Frank Baumann (Tübingen, Germany) for comments on this manuscript, Stephan Käser, Götz Heilbronner, Judith Finkbeiner, Anika Bühler, Stefan Grathwohl, and Nick Varvel (Tübingen, Germany) for the help with the immunoassays and immunostaining, and all the other members of our laboratory for their contributions. The generous donation of the pFTAA dye from Peter Nilsson (Linköping, Sweden) is greatly appreciated. The advice and help of Bruce Lamb with the R1.40 mice is greatly acknowledged.
- Correspondence should be addressed to either Yvonne S. Eisele or Mathias Jucker at the above address. yvonne.s.eisele{at}gmail.com or mathias.jucker{at}uni-tuebingen.de
