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Articles, Cellular/Molecular

Interplay between Synchronization of Multivesicular Release and Recruitment of Additional Release Sites Support Short-Term Facilitation at Hippocampal Mossy Fiber to CA3 Pyramidal Cells Synapses

Simon Chamberland, Alesya Evstratova and Katalin Tóth
Journal of Neuroscience 13 August 2014, 34 (33) 11032-11047; DOI: https://doi.org/10.1523/JNEUROSCI.0847-14.2014
Simon Chamberland
Quebec Mental Health Institute, Department of Psychiatry and Neuroscience, Laval University, Quebec City, Quebec, Canada, G1J 2G3
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Alesya Evstratova
Quebec Mental Health Institute, Department of Psychiatry and Neuroscience, Laval University, Quebec City, Quebec, Canada, G1J 2G3
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Katalin Tóth
Quebec Mental Health Institute, Department of Psychiatry and Neuroscience, Laval University, Quebec City, Quebec, Canada, G1J 2G3
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0847-14.2014
PubMed 
25122902
Published By 
Society for Neuroscience
History 
  • Received February 27, 2014
  • Revision received June 7, 2014
  • Accepted June 27, 2014
  • First published August 13, 2014.
  • Version of record published August 13, 2014.
Copyright & Usage 
Copyright © 2014 the authors 0270-6474/14/3411032-16$15.00/0

Author Information

  1. Simon Chamberland,
  2. Alesya Evstratova, and
  3. Katalin Tóth
  1. Quebec Mental Health Institute, Department of Psychiatry and Neuroscience, Laval University, Quebec City, Quebec, Canada, G1J 2G3
View Full Text

Author contributions

  1. Author contributions: S.C. and K.T. designed research; S.C., A.E., and K.T. performed research; S.C., A.E., and K.T. analyzed data; S.C. and K.T. wrote the paper.

Disclosures

    • Received February 27, 2014.
    • Revision received June 7, 2014.
    • Accepted June 27, 2014.
  • This work was supported by a Canadian Institutes of Health Research operating grant (K.T.), a Natural Sciences and Engineering Research Council of Canada scholarship (S.C.), and a Centre thématique de recherche en neurosciences fellowship (A.E.). We thank Dr. Yves De Koninck for providing access to the acousto-optic deflector-based two-photon imaging system, Dr. Stéphane Dieudonné (Paris, France) for advice with RAMP and two-photon calcium imaging, and Benjamin Mathieu (Paris, France) for expert help and development with the imaging software.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Katalin Tóth, Quebec Mental Health Institute, Department of Psychiatry and Neuroscience, Faculty of Medicine, Laval University, 2601 chemin de la Canardière, Quebec City, Quebec, Canada, G1J 2G3. toth.katalin{at}crulrg.ulaval.ca

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The Journal of Neuroscience: 34 (33)
Journal of Neuroscience
Vol. 34, Issue 33
13 Aug 2014
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Interplay between Synchronization of Multivesicular Release and Recruitment of Additional Release Sites Support Short-Term Facilitation at Hippocampal Mossy Fiber to CA3 Pyramidal Cells Synapses
Simon Chamberland, Alesya Evstratova, Katalin Tóth
Journal of Neuroscience 13 August 2014, 34 (33) 11032-11047; DOI: 10.1523/JNEUROSCI.0847-14.2014

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Interplay between Synchronization of Multivesicular Release and Recruitment of Additional Release Sites Support Short-Term Facilitation at Hippocampal Mossy Fiber to CA3 Pyramidal Cells Synapses
Simon Chamberland, Alesya Evstratova, Katalin Tóth
Journal of Neuroscience 13 August 2014, 34 (33) 11032-11047; DOI: 10.1523/JNEUROSCI.0847-14.2014
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Keywords

  • mossy fiber
  • multivesicular release
  • presynaptic calcium
  • short-term facilitation

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