An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

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¹Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305-5125,
²The Vivian L. Smith Department of Neurosurgery, University of Texas Medical School at Houston, Houston, Texas 77057,
³Center for Stem Cell and Regenerative Medicine, University of Texas Brown Institute of Molecular Medicine, Houston, Texas 77057,
⁴Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, New York 10032,
⁵Department of Anatomy, University of California, San Francisco, San Francisco, California 94143-0452,
⁶Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, Victoria, Australia 3010, and
⁷Department of Systems Biology,
⁸Center for Motor Neuron Biology and Disease, and
⁹Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York 10032

Author contributions: Y.Z., S.A.S., M.L.B., R.D., T.M., B.A.B., and J.Q.W. designed research; Y.Z., S.A.S., M.L.B., A.R.S., C.C., N.R., and S.D. performed research; S.A.L. and C.Z. contributed unpublished reagents/analytic tools; Y.Z., K.C., S.A.S., M.L.B., S.O., H.P.P., and P.G. analyzed data; Y.Z., S.A.S., and B.A.B. wrote the paper.
↵*Y.Z., K.C., and S.A.S. contributed equally to this work.
↵†B.A.B. and J.Q.W. contributed equally to this work.

This work is supported by National Institutes of Health Grants R01 MH09955501 and R01 NS08170301 (B.A.B.), T32GM007365 with additional support from Stanford School of Medicine and its Medical Scientist Training Program (S.S.), and R00 GM95713 (C.Z.), a Berry Postdoctoral Fellowship (Y.Z.), and a National Health and Medical Research Council of Australia C. J. Martin Fellowship (S.L.). J.Q.W., K.C., and S.D. are supported by National Institutes of Health and the Staman Ogilvie Fund–Memorial Hermann Foundation. We thank Dr. Dritan Agalliu for Cldn5 expression plasmid and Vincent and Stella Coates for their generous support.
The authors declare no competing financial interests.
Correspondence should be addressed to either of the following: Ye Zhang, Stanford University School of Medicine, Department of Neurobiology, 299 Campus Drive, Fairchild Building, Stanford, California 94305-5125, zhangye{at}stanford.edu; or Jia Qian Wu, University of Texas Medical School, 1825 Pressler Street, SRB-630.01, Houston, TX 77030. jiaqian.wu{at}uth.tmc.edu

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