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Articles, Behavioral/Cognitive

Three Mechanisms by which Striatal Denervation Causes Breakdown of Dopamine Signaling

Jakob K. Dreyer
Journal of Neuroscience 10 September 2014, 34 (37) 12444-12456; https://doi.org/10.1523/JNEUROSCI.1458-14.2014
Jakob K. Dreyer
Department of Neuroscience and Pharmacology, University of Copenhagen, 2200 Copenhagen, Denmark
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1458-14.2014
PubMed 
25209283
Published By 
Society for Neuroscience
History 
  • Received April 10, 2014
  • Revision received July 11, 2014
  • Accepted July 30, 2014
  • First published September 10, 2014.
  • Version of record published September 10, 2014.
Copyright & Usage 
Copyright © 2014 the authors 0270-6474/14/3412444-13$15.00/0

Author Information

  1. Jakob K. Dreyer
  1. Department of Neuroscience and Pharmacology, University of Copenhagen, 2200 Copenhagen, Denmark
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Author contributions

  1. Author contributions: J.K.D. designed research; J.K.D. performed research; J.K.D. contributed unpublished reagents/analytic tools; J.K.D. analyzed data; J.K.D. wrote the paper.

Disclosures

    • Received April 10, 2014.
    • Revision received July 11, 2014.
    • Accepted July 30, 2014.
  • This work was supported by the Lundbeck Foundation. I also thank Jeff A. Beeler (City University of New York, New York, NY) and Mark Humphries (University of Manchester, Manchester, United Kingdom) for commenting on an early version of this work.

  • The author declares no competing financial interests.

  • Correspondence should be addressed to Jakob K. Dreyer, Department of Neuroscience and Pharmacology, University of Copenhagen, Blegdamsvej 3, 24.3.45, 2200 Copenhagen, Denmark. jakobdr{at}sund.ku.dk

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The Journal of Neuroscience: 34 (37)
Journal of Neuroscience
Vol. 34, Issue 37
10 Sep 2014
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Three Mechanisms by which Striatal Denervation Causes Breakdown of Dopamine Signaling
Jakob K. Dreyer
Journal of Neuroscience 10 September 2014, 34 (37) 12444-12456; DOI: 10.1523/JNEUROSCI.1458-14.2014

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Three Mechanisms by which Striatal Denervation Causes Breakdown of Dopamine Signaling
Jakob K. Dreyer
Journal of Neuroscience 10 September 2014, 34 (37) 12444-12456; DOI: 10.1523/JNEUROSCI.1458-14.2014
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Keywords

  • supersensitivity
  • compensation
  • D2 receptor
  • dopamine
  • Parkinson's disease

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