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Cover legend: Coronal section of a mouse brain containing the inhibitory neuromodulator hM4D in GABA neurons (red) of the ventral hippocampus, overlayed with DAPI nuclear staining (blue). Silencing of neural activity mediated by hM4D in either parvalbumin-positive or GAD65-positive GABA neurons produced distinct behaviors related to schizophrenia. For more details, see the article by Nguyen et al. (pages 14948–14960).