Cover legend: Longitudinal sections of sciatic nerves from neuropathic PMP22-null mice were double-labeled with the lipid raft marker cholera toxin subunit β (in red) and phalloidin (in green) to illustrate the severe disruption of lipid raft and actin network in myelinating Schwann cells lacking PMP22. Nuclei are shown in blue. For more details, see the article by Lee et al. (pages 16140–16152).