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Articles, Cellular/Molecular

Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton

Yuewen Chen, Fanny C.F. Ip, Lei Shi, Zhe Zhang, Huibin Tang, Yu Pong Ng, Wen-Cai Ye, Amy K.Y. Fu and Nancy Y. Ip
Journal of Neuroscience 12 February 2014, 34 (7) 2413-2421; https://doi.org/10.1523/JNEUROSCI.3226-13.2014
Yuewen Chen
1JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, Jinan University, Guangzhou 510632, Guangdong, China,
2Division of Life Science and
3State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China, and
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Fanny C.F. Ip
1JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, Jinan University, Guangzhou 510632, Guangdong, China,
2Division of Life Science and
3State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China, and
4Guangdong Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, Guangdong, China
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Lei Shi
1JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, Jinan University, Guangzhou 510632, Guangdong, China,
2Division of Life Science and
3State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China, and
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Zhe Zhang
2Division of Life Science and
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Huibin Tang
2Division of Life Science and
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Yu Pong Ng
2Division of Life Science and
3State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China, and
4Guangdong Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, Guangdong, China
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Wen-Cai Ye
1JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, Jinan University, Guangzhou 510632, Guangdong, China,
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Amy K.Y. Fu
1JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, Jinan University, Guangzhou 510632, Guangdong, China,
2Division of Life Science and
3State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China, and
4Guangdong Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, Guangdong, China
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Nancy Y. Ip
1JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, Jinan University, Guangzhou 510632, Guangdong, China,
2Division of Life Science and
3State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China, and
4Guangdong Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, Guangdong, China
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.3226-13.2014
PubMed 
24523531
Published By 
Society for Neuroscience
History 
  • Received July 25, 2013
  • Revision received December 22, 2013
  • Accepted December 28, 2013
  • First published February 12, 2014.
  • Version of record published February 12, 2014.
Copyright & Usage 
Copyright © 2014 the authors 0270-6474/14/342413-09$15.00/0

Author Information

  1. Yuewen Chen1,2,3,
  2. Fanny C.F. Ip1,2,3,4,
  3. Lei Shi1,2,3,
  4. Zhe Zhang2,
  5. Huibin Tang2,
  6. Yu Pong Ng2,3,4,
  7. Wen-Cai Ye1,
  8. Amy K.Y. Fu1,2,3,4, and
  9. Nancy Y. Ip1,2,3,4
  1. 1JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, Jinan University, Guangzhou 510632, Guangdong, China,
  2. 2Division of Life Science and
  3. 3State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China, and
  4. 4Guangdong Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, Guangdong, China
View Full Text

Author contributions

  1. Author contributions: Y.C., Y.P.N., A.K.Y.F., and N.Y.I. designed research; Y.C., F.C.F.I., Z.Z., and H.T. performed research; W.-c.Y. and N.Y.I. contributed unpublished reagents/analytic tools; Y.C., F.C.F.I., H.T., Y.P.N., A.K.Y.F., and N.Y.I. analyzed data; Y.C., F.C.F.I., L.S., A.K.Y.F., and N.Y.I. wrote the paper.

Disclosures

    • Received July 25, 2013.
    • Revision received December 22, 2013.
    • Accepted December 28, 2013.
  • This work was supported in part by the Research Grants Council of Hong Kong (HKUST661109 and HKUST661309; Theme-based Research Scheme T13-607/12R), the National Key Basic Research Program of China (2013CB530900), the National Natural Science Foundation of China for Young Scholars of China (Grant 81101015), the Innovation and Technology Fund for State Key Laboratory (ITCPT/17-9), the Shenzhen Peacock Plan, and the S.H. Ho Foundation.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Nancy Y. Ip, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China. boip{at}ust.hk

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Jan 20188204
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The Journal of Neuroscience: 34 (7)
Journal of Neuroscience
Vol. 34, Issue 7
12 Feb 2014
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Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton
Yuewen Chen, Fanny C.F. Ip, Lei Shi, Zhe Zhang, Huibin Tang, Yu Pong Ng, Wen-Cai Ye, Amy K.Y. Fu, Nancy Y. Ip
Journal of Neuroscience 12 February 2014, 34 (7) 2413-2421; DOI: 10.1523/JNEUROSCI.3226-13.2014

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Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton
Yuewen Chen, Fanny C.F. Ip, Lei Shi, Zhe Zhang, Huibin Tang, Yu Pong Ng, Wen-Cai Ye, Amy K.Y. Fu, Nancy Y. Ip
Journal of Neuroscience 12 February 2014, 34 (7) 2413-2421; DOI: 10.1523/JNEUROSCI.3226-13.2014
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Keywords

  • acetylcholine
  • actin-binding proteins
  • actin cytoskeleton
  • Coronin 6

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