Brief Communications

Postsynaptic FMRP Promotes the Pruning of Cell-to-Cell Connections among Pyramidal Neurons in the L5A Neocortical Network

Ankur B. Patel, Kristofer W. Loerwald, Kimberly M. Huber and Jay R. Gibson
Journal of Neuroscience 26 February 2014, 34 (9) 3413-3418; https://doi.org/10.1523/JNEUROSCI.2921-13.2014

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2921-13.2014
PubMed 
24573297
Published By 
Society for Neuroscience
History 
  • Received July 9, 2013
  • Revision received January 9, 2014
  • Accepted January 29, 2014
  • First published February 26, 2014.
  • Version of record published February 26, 2014.
Copyright & Usage 
Copyright © 2014 the authors 0270-6474/14/343413-06$15.00/0

Author Information

  1. Ankur B. Patel,
  2. Kristofer W. Loerwald,
  3. Kimberly M. Huber, and
  4. Jay R. Gibson
  1. University of Texas Southwestern Medical Center, Department of Neuroscience, Dallas, Texas 75390-9111
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Author contributions

  1. Author contributions: A.B.P., K.M.H., and J.R.G. designed research; A.B.P. and K.W.L. performed research; A.B.P., K.W.L., and J.R.G. analyzed data; A.B.P., K.M.H., and J.R.G. wrote the paper.

Disclosures

    • Received July 9, 2013.
    • Revision received January 9, 2014.
    • Accepted January 29, 2014.

  • This work was supported by the National Institutes of Health (Grant HD056370 and linked ARRA administrative supplement to J.R.G., Grant HD052731 to K.M.H., and Training Grant 1T32NS069562 to A.B.P.) and Autism Speaks (K.M.H.). We thank Nicole Cabalo for technical assistance with mice.

  • Correspondence should be addressed to Jay R. Gibson, University of Texas, Southwestern Medical Center, Department of Neuroscience, Box 9111, Dallas, TX 75390-9111. Jay.Gibson{at}UTSouthwestern.edu

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Total2321398672
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Postsynaptic FMRP Promotes the Pruning of Cell-to-Cell Connections among Pyramidal Neurons in the L5A Neocortical Network
Ankur B. Patel, Kristofer W. Loerwald, Kimberly M. Huber, Jay R. Gibson
Journal of Neuroscience 26 February 2014, 34 (9) 3413-3418; DOI: 10.1523/JNEUROSCI.2921-13.2014
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