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Brief Communications

Visual Fixation in Human Newborns Correlates with Extensive White Matter Networks and Predicts Long-Term Neurocognitive Development

Susanna Stjerna, Viljami Sairanen, Riitta Gröhn, Sture Andersson, Marjo Metsäranta, Aulikki Lano and Sampsa Vanhatalo
Journal of Neuroscience 25 March 2015, 35 (12) 4824-4829; DOI: https://doi.org/10.1523/JNEUROSCI.5162-14.2015
Susanna Stjerna
1Departments of Clinical Neurophysiology, HUS Medical Imaging Center, and Neurological Sciences,
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Viljami Sairanen
1Departments of Clinical Neurophysiology, HUS Medical Imaging Center, and Neurological Sciences,
4Physics, University of Helsinki and Helsinki University Central Hospital, Helsinki 00029, Finland
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Riitta Gröhn
1Departments of Clinical Neurophysiology, HUS Medical Imaging Center, and Neurological Sciences,
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Sture Andersson
2Pediatrics,
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Marjo Metsäranta
2Pediatrics,
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Aulikki Lano
3Child Neurology, and
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Sampsa Vanhatalo
1Departments of Clinical Neurophysiology, HUS Medical Imaging Center, and Neurological Sciences,
2Pediatrics,
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    Figure 1.

    Relation of newborn VF and GB to neurocognitive outcomes at 2 and 5 years. A, Gvmi at 2 years (Group 1) according to newborn VF and GB scores (mean±confidence interval 95%). Ab, Ad, Findings from categorical regression analysis (Q, quantifications; estimated ± 95% confidence intervals). Q, Quantifications of Gvmi. B, ViR and VMI at 5 years (Group 2) according to newborn VF scores. C, Models combining visual and motor performance (left, Group 1; right, Group 2) show the preferential relationship from newborn VF to visual cognitive outcomes. DQ, Developmental quotient. Significant findings are indicated with an asterisk.

  • Figure 2.
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    Figure 2.

    Structural correlates of newborn VF and GB. A, White matter skeleton is depicted in green, and voxels with significant correlation to VF (top) or GB (bottom) are depicted in blue. B, Mean FA values of FA skeleton voxels within each region of interest (ROI, blue boxes).

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The Journal of Neuroscience: 35 (12)
Journal of Neuroscience
Vol. 35, Issue 12
25 Mar 2015
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Visual Fixation in Human Newborns Correlates with Extensive White Matter Networks and Predicts Long-Term Neurocognitive Development
Susanna Stjerna, Viljami Sairanen, Riitta Gröhn, Sture Andersson, Marjo Metsäranta, Aulikki Lano, Sampsa Vanhatalo
Journal of Neuroscience 25 March 2015, 35 (12) 4824-4829; DOI: 10.1523/JNEUROSCI.5162-14.2015

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Visual Fixation in Human Newborns Correlates with Extensive White Matter Networks and Predicts Long-Term Neurocognitive Development
Susanna Stjerna, Viljami Sairanen, Riitta Gröhn, Sture Andersson, Marjo Metsäranta, Aulikki Lano, Sampsa Vanhatalo
Journal of Neuroscience 25 March 2015, 35 (12) 4824-4829; DOI: 10.1523/JNEUROSCI.5162-14.2015
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Keywords

  • attention
  • biomarker
  • DTI
  • early cognition
  • neonatal
  • Visual function

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