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Articles, Neurobiology of Disease

The Contribution of Raised Intraneuronal Chloride to Epileptic Network Activity

Hannah Alfonsa, Edward M. Merricks, Neela K. Codadu, Mark O. Cunningham, Karl Deisseroth, Claudia Racca and Andrew J. Trevelyan
Journal of Neuroscience 20 May 2015, 35 (20) 7715-7726; DOI: https://doi.org/10.1523/JNEUROSCI.4105-14.2015
Hannah Alfonsa
1Institute of Neuroscience, Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom, and
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Edward M. Merricks
1Institute of Neuroscience, Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom, and
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Neela K. Codadu
1Institute of Neuroscience, Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom, and
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Mark O. Cunningham
1Institute of Neuroscience, Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom, and
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Karl Deisseroth
2Departments of Bioengineering and 3Psychiatry and 4Howard Hughes Medical Institute, Stanford University, Stanford, California 94305
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Claudia Racca
1Institute of Neuroscience, Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom, and
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Andrew J. Trevelyan
1Institute of Neuroscience, Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom, and
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The Journal of Neuroscience: 35 (20)
Journal of Neuroscience
Vol. 35, Issue 20
20 May 2015
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The Contribution of Raised Intraneuronal Chloride to Epileptic Network Activity
Hannah Alfonsa, Edward M. Merricks, Neela K. Codadu, Mark O. Cunningham, Karl Deisseroth, Claudia Racca, Andrew J. Trevelyan
Journal of Neuroscience 20 May 2015, 35 (20) 7715-7726; DOI: 10.1523/JNEUROSCI.4105-14.2015

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The Contribution of Raised Intraneuronal Chloride to Epileptic Network Activity
Hannah Alfonsa, Edward M. Merricks, Neela K. Codadu, Mark O. Cunningham, Karl Deisseroth, Claudia Racca, Andrew J. Trevelyan
Journal of Neuroscience 20 May 2015, 35 (20) 7715-7726; DOI: 10.1523/JNEUROSCI.4105-14.2015
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Keywords

  • chloride
  • fast spiking interneuron
  • high frequency oscillations
  • neocortex
  • pyramidal neuron
  • seizure

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