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Featured ArticleArticles, Behavioral/Cognitive

Noradrenaline and Dopamine Neurons in the Reward/Effort Trade-Off: A Direct Electrophysiological Comparison in Behaving Monkeys

Chiara Varazzani, Aurore San-Galli, Sophie Gilardeau and Sebastien Bouret
Journal of Neuroscience 20 May 2015, 35 (20) 7866-7877; DOI: https://doi.org/10.1523/JNEUROSCI.0454-15.2015
Chiara Varazzani
1Motivation, Brain, and Behavior Team, Institut du Cerveau et de la Moelle Épinière, 75013 Paris, France,
2Frontières du Vivant, Université Sorbonne Paris Cité, Paris, France, and
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Aurore San-Galli
1Motivation, Brain, and Behavior Team, Institut du Cerveau et de la Moelle Épinière, 75013 Paris, France,
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Sophie Gilardeau
3Institute for Translational Neuroscience of Paris IHU-A-ICM, 75013 Paris, France
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Sebastien Bouret
1Motivation, Brain, and Behavior Team, Institut du Cerveau et de la Moelle Épinière, 75013 Paris, France,
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0454-15.2015
Published By 
Society for Neuroscience
History 
  • Received February 3, 2015
  • Revision received March 24, 2015
  • Accepted April 2, 2015
  • First published May 20, 2015.
  • Version of record published May 20, 2015.
Copyright & Usage 
Copyright © 2015 the authors 0270-6474/15/357866-12$15.00/0

Author Information

  1. Chiara Varazzani1,2,
  2. Aurore San-Galli1,
  3. Sophie Gilardeau3, and
  4. Sebastien Bouret1
  1. 1Motivation, Brain, and Behavior Team, Institut du Cerveau et de la Moelle Épinière, 75013 Paris, France,
  2. 2Frontières du Vivant, Université Sorbonne Paris Cité, Paris, France, and
  3. 3Institute for Translational Neuroscience of Paris IHU-A-ICM, 75013 Paris, France
View Full Text

Author contributions

  1. Author contributions: C.V., A.S.-G., and S.B. designed research; C.V., A.S.-G., S.G., and S.B. performed research; C.V. and S.B. analyzed data; C.V. and S.B. wrote the paper.

Disclosures

    • Received February 3, 2015.
    • Revision received March 24, 2015.
    • Accepted April 2, 2015.
  • This work was supported by a starting grant funded by the European Research Council (ERC-BioMotiv). C.V. received a doctoral fellowship from the École Doctorale Frontières du Vivant. We thank Susan Sara, Brian Lau, Takafumi Minamimoto, Thomas Andrillon, and Mathias Pessiglione for helpful comments on early versions of the manuscript and Morgane Monfort, Serban Morosan, and the personnel from the ICM primate facility for assistance with surgery and veterinary procedures.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Sebastien Bouret, Motivation, Brain, and Behavior Team, Institut du Cerveau et de la Moelle Épinière, Hôpital Pitié Salpêtrière, 47 Boulevard de d'Hôpital, 75013 Paris, France. sebastien.bouret{at}icm-institute.org

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The Journal of Neuroscience: 35 (20)
Journal of Neuroscience
Vol. 35, Issue 20
20 May 2015
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Noradrenaline and Dopamine Neurons in the Reward/Effort Trade-Off: A Direct Electrophysiological Comparison in Behaving Monkeys
Chiara Varazzani, Aurore San-Galli, Sophie Gilardeau, Sebastien Bouret
Journal of Neuroscience 20 May 2015, 35 (20) 7866-7877; DOI: 10.1523/JNEUROSCI.0454-15.2015

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Noradrenaline and Dopamine Neurons in the Reward/Effort Trade-Off: A Direct Electrophysiological Comparison in Behaving Monkeys
Chiara Varazzani, Aurore San-Galli, Sophie Gilardeau, Sebastien Bouret
Journal of Neuroscience 20 May 2015, 35 (20) 7866-7877; DOI: 10.1523/JNEUROSCI.0454-15.2015
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Keywords

  • choice
  • decision
  • locus coeruleus
  • motivation
  • pupil
  • substantia nigra

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