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Featured ArticleArticles, Systems/Circuits

Glucose Induces Slow-Wave Sleep by Exciting the Sleep-Promoting Neurons in the Ventrolateral Preoptic Nucleus: A New Link between Sleep and Metabolism

Christophe Varin, Armelle Rancillac, Hélène Geoffroy, Sébastien Arthaud, Patrice Fort and Thierry Gallopin
Journal of Neuroscience 8 July 2015, 35 (27) 9900-9911; DOI: https://doi.org/10.1523/JNEUROSCI.0609-15.2015
Christophe Varin
1Brain Plasticity Unit, Sleep Neuronal Networks Team, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8249, 75005 Paris, France,
2Ecole Supérieure de Physique et de Chimie Industrielles ParisTech, 75005 Paris, France,
3Physiopathologie des Réseaux Neuronaux Responsables du Cycle Veille-Sommeil Team, INSERM, U1028, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5292, Lyon Neuroscience Research Center, 69372 Lyon, France, and
4University Lyon 1, 69000 Lyon, France
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Armelle Rancillac
1Brain Plasticity Unit, Sleep Neuronal Networks Team, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8249, 75005 Paris, France,
2Ecole Supérieure de Physique et de Chimie Industrielles ParisTech, 75005 Paris, France,
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Hélène Geoffroy
1Brain Plasticity Unit, Sleep Neuronal Networks Team, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8249, 75005 Paris, France,
2Ecole Supérieure de Physique et de Chimie Industrielles ParisTech, 75005 Paris, France,
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Sébastien Arthaud
3Physiopathologie des Réseaux Neuronaux Responsables du Cycle Veille-Sommeil Team, INSERM, U1028, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5292, Lyon Neuroscience Research Center, 69372 Lyon, France, and
4University Lyon 1, 69000 Lyon, France
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Patrice Fort
3Physiopathologie des Réseaux Neuronaux Responsables du Cycle Veille-Sommeil Team, INSERM, U1028, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5292, Lyon Neuroscience Research Center, 69372 Lyon, France, and
4University Lyon 1, 69000 Lyon, France
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Thierry Gallopin
1Brain Plasticity Unit, Sleep Neuronal Networks Team, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8249, 75005 Paris, France,
2Ecole Supérieure de Physique et de Chimie Industrielles ParisTech, 75005 Paris, France,
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0609-15.2015
Published By 
Society for Neuroscience
History 
  • Received February 13, 2015
  • Revision received May 29, 2015
  • Accepted June 2, 2015
  • First published July 8, 2015.
  • Version of record published July 8, 2015.
Copyright & Usage 
Copyright © 2015 the authors 0270-6474/15/359900-12$15.00/0

Author Information

  1. Christophe Varin1,2,3,4,
  2. Armelle Rancillac1,2,
  3. Hélène Geoffroy1,2,
  4. Sébastien Arthaud3,4,
  5. Patrice Fort3,4, and
  6. Thierry Gallopin1,2
  1. 1Brain Plasticity Unit, Sleep Neuronal Networks Team, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8249, 75005 Paris, France,
  2. 2Ecole Supérieure de Physique et de Chimie Industrielles ParisTech, 75005 Paris, France,
  3. 3Physiopathologie des Réseaux Neuronaux Responsables du Cycle Veille-Sommeil Team, INSERM, U1028, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5292, Lyon Neuroscience Research Center, 69372 Lyon, France, and
  4. 4University Lyon 1, 69000 Lyon, France
View Full Text

Author contributions

  1. Author contributions: C.V., P.F., and T.G. designed research; C.V., A.R., H.G., S.A., and T.G. performed research; C.V., S.A., and T.G. analyzed data; C.V., A.R., P.F., and T.G. wrote the paper.

Disclosures

    • Received February 13, 2015.
    • Revision received May 29, 2015.
    • Accepted June 2, 2015.
  • This work was supported by the Fondation Pierre-Gilles de Gennes pour la Recherché (Grant ANR-12-JSV4-0001-01), the Centre National de la Recherche Scientifique, and Ecole Supérieure de Physique et de Chimie Industrielles ParisTech. We thank Brandon Loveall of Improvence for English proofreading and Karim Benchenane for invaluable comments on the manuscript.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Thierry Gallopin, PhD, Brain Plasticity Unit, CNRS UMR 8249, ESPCI ParisTech, 10 rue Vauquelin, 75005 Paris, France. thierry.gallopin{at}espci.fr

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Jan 20181417715
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Apr 2018155114
May 201810654
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Jul 20185335
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Apr 20219508
May 202185134
Jun 202145021
Jul 202174219
Aug 202174523
Sep 202193919
Oct 2021105737
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Apr 202275622
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Apr 2023103515
May 2023103412
Jun 20239509
Jul 202353920
Aug 202352111
Sep 20238597
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Total 202389483152
Total5813592974
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The Journal of Neuroscience: 35 (27)
Journal of Neuroscience
Vol. 35, Issue 27
8 Jul 2015
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Glucose Induces Slow-Wave Sleep by Exciting the Sleep-Promoting Neurons in the Ventrolateral Preoptic Nucleus: A New Link between Sleep and Metabolism
Christophe Varin, Armelle Rancillac, Hélène Geoffroy, Sébastien Arthaud, Patrice Fort, Thierry Gallopin
Journal of Neuroscience 8 July 2015, 35 (27) 9900-9911; DOI: 10.1523/JNEUROSCI.0609-15.2015

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Glucose Induces Slow-Wave Sleep by Exciting the Sleep-Promoting Neurons in the Ventrolateral Preoptic Nucleus: A New Link between Sleep and Metabolism
Christophe Varin, Armelle Rancillac, Hélène Geoffroy, Sébastien Arthaud, Patrice Fort, Thierry Gallopin
Journal of Neuroscience 8 July 2015, 35 (27) 9900-9911; DOI: 10.1523/JNEUROSCI.0609-15.2015
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Keywords

  • glucose
  • homeostasis
  • hypothalamus
  • polysomnography
  • preoptic nucleus
  • sleep

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