Article Information
- Received June 1, 2015
- Revision received July 6, 2015
- Accepted July 23, 2015
- First published September 2, 2015.
- Version of record published September 2, 2015.
Author Information
Author contributions
Author contributions: K.K., A.F., and M.N. designed research; K.K., A.F., and R.S. performed research; K.K., A.F., and M.N. analyzed data; K.K., A.F., and M.N. wrote the paper.
Disclosures
- Received June 1, 2015.
- Revision received July 6, 2015.
- Accepted July 23, 2015.
This work was supported by Adaptable and Seamless Technology Transfer Program through Target-driven R&D (A-STEP), Japan Science and Technology Agency (M.N.); Imaging Science Project of the Center for Novel Science Initiatives; National Institutes of Natural Sciences (A.F.); and the Japan Society for the Promotion of Science (KAKENHI Grants 24700387 and 26830050 to K.K.). Micro-CT analyses were performed at the Model Animal Research Facility of the National Institute for Basic Biology (NIBB). Immunofluorescence photomicrograph images were acquired at the Spectrography and Bioimaging Facility, NIBB Core Research Facilities. We thank M. Katsuki for providing us with p53-deficient mice, Y. Isoshima and N. Nakanishi for technical assistance, and A. Kodama for secretarial assistance.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Masaharu Noda, Division of Molecular Neurobiology, National Institute for Basic Biology, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan. madon{at}nibb.ac.jp