Article Information
- Received April 24, 2015
- Revision received July 27, 2015
- Accepted August 9, 2015
- First published September 9, 2015.
- Version of record published September 9, 2015.
Author Information
- Meltem Sevgi1,
- Lionel Rigoux1,
- Anne B. Kühn1,2,
- Jan Mauer3,
- Leonhard Schilbach4,5,
- Martin E. Hess1,
- Theo O.J. Gruendler4,7,8,
- Markus Ullsperger6,8,9,
- Klaas Enno Stephan1,10,11,
- Jens C. Brüning1,2,12,*, and
- Marc Tittgemeyer1,*
- 1Max Planck Institute for Metabolism Research, 50931 Cologne, Germany,
- 2Center for Endocrinology, Diabetes and Preventive Medicine, University Hospital of Cologne, 50931 Cologne, Germany,
- 3Weill Cornell Medical College, Department of Pharmacology, New York, New York 10021,
- 4Department of Psychiatry, University Hospital of Cologne, 50937 Cologne, Germany,
- 5Max-Planck-Institute of Psychiatry, 80804 Munich, Germany,
- 6Departments of Neuropsychology and
- 7Economics, Otto-von-Guericke-University Magdeburg, 39106 Magdeburg, Germany,
- 8Center for Behavioral Brain Sciences, 39106 Magdeburg, Germany,
- 9Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, 6525EZ Nijmegen, The Netherlands,
- 10Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology, 8032 Zurich, Switzerland,
- 11Wellcome Trust Centre for Neuroimaging, University College London, London WC1N 3BG, United Kingdom, and
- 12Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, 50931 Cologne, Germany
Author contributions
Author contributions: J.C.B. and M.T. designed research; M.S., L.R., A.B.K., and L.S. performed research; M.U. and K.E.S. contributed unpublished reagents/analytic tools; M.S., L.R., J.M., M.E.H., T.O.J.G., and M.T. analyzed data; J.C.B. and M.T. wrote the paper.
↵*J.C.B. and M.T. contributed equally to the present study.
Disclosures
- Received April 24, 2015.
- Revision received July 27, 2015.
- Accepted August 9, 2015.
This study was carried out within the framework of the German Competence Network Obesity (01GI1122A). Furthermore, M.T., T.O.J.G., and M.U. were supported by the German Research Foundation in the Clinical Research Group 219. L.S., K.E.S., J.C.B., and M.T. were supported by the German Research Foundation in the Transregional Collaborative Research Center 134. K.E.S. was supported by the René and Susanne Braginsky Foundation. We thank Nadine Spenrath for excellent technical assistance; and Nico Bunzeck and Emrah Düzel for providing the anatomical masks for delineating the VTA/SN.
The authors declare no competing financial interests.
- Correspondence should be addressed to either Dr. Marc Tittgemeyer or Dr. Jens Brüning, Max-Planck-Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany. tittgemeyer{at}sf.mpg.de or bruening{at}sf.mpg.de
