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Articles, Neurobiology of Disease

Lymphocytes from Chronically Stressed Mice Confer Antidepressant-Like Effects to Naive Mice

Rebecca A. Brachman, Michael L. Lehmann, Dragan Maric and Miles Herkenham
Journal of Neuroscience 28 January 2015, 35 (4) 1530-1538; DOI: https://doi.org/10.1523/JNEUROSCI.2278-14.2015
Rebecca A. Brachman
1Section on Functional Neuroanatomy, Laboratory of Cellular and Molecular Regulation, and
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Michael L. Lehmann
1Section on Functional Neuroanatomy, Laboratory of Cellular and Molecular Regulation, and
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Dragan Maric
2NINDS Flow Cytometry Core Facility, NIH–DHHS, Bethesda, Maryland 20892
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Miles Herkenham
1Section on Functional Neuroanatomy, Laboratory of Cellular and Molecular Regulation, and
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2278-14.2015
PubMed 
25632130
Published By 
Society for Neuroscience
History 
  • Received May 27, 2014
  • Revision received November 26, 2014
  • Accepted December 3, 2014
  • First published January 28, 2015.
  • Version of record published January 28, 2015.
Copyright & Usage 
Copyright © 2015 the authors 0270-6474/15/351530-09$15.00/0

Author Information

  1. Rebecca A. Brachman1,*,
  2. Michael L. Lehmann1,*,
  3. Dragan Maric2, and
  4. Miles Herkenham1
  1. 1Section on Functional Neuroanatomy, Laboratory of Cellular and Molecular Regulation, and
  2. 2NINDS Flow Cytometry Core Facility, NIH–DHHS, Bethesda, Maryland 20892
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Author contributions

  1. Author contributions: R.A.B. and M.L.L. designed research; R.A.B. and M.L.L. performed research; D.M. contributed unpublished reagents/analytic tools; M.L.L. and D.M. analyzed data; M.H. wrote the paper.

  2. ↵*R.A.B. and M.L.L. contributed equally to this work.

Disclosures

    • Received May 27, 2014.
    • Revision received November 26, 2014.
    • Accepted December 3, 2014.
  • The work was supported by the National Institute of Mental Health (NIMH) Intramural Research Program, Z01 MH001090. We thank Heather Kalish, National Institute of Biomedical Imaging and Bioengineering, and Samuel Listwak; Rachel Scheinert; Mitra Haeri; and Monica Mehta, Section on Functional Neuroanatomy, NIMH, for performing assays. M.H. acknowledges his long association with the late Candace B. Pert and their discussions of the communication network between brain and body.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Miles Herkenham, Section on Functional Neuroanatomy, LCMR, NIMH, Building 35, Room 1C913, Bethesda, MD 20892. herkenh{at}mail.nih.gov

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Jan 2015178377226
Feb 20151551223326
Mar 20155947589
Apr 20152427464
May 20152025348
Jun 20151435327
Jul 20151124029
Aug 20151365437
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Jul 2017173532
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Sep 2017134230
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Total 2017179596312
Jan 20185657
Feb 2018108014
Mar 2018256314
Apr 2018107623
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Jun 201876615
Jul 2018134632
Aug 2018105115
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Total 2018123775222
Jan 201986715
Feb 201922369
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Apr 2019215531
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Jun 2019116419
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Total 2019178777222
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May 20201313826
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Total 2021109705293
Jan 202243817
Feb 202213912
Mar 202275529
Apr 202238731
May 2022114425
Jun 202225225
Jul 2022032
Total 202228318141
Total646556222933
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The Journal of Neuroscience: 35 (4)
Journal of Neuroscience
Vol. 35, Issue 4
28 Jan 2015
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Lymphocytes from Chronically Stressed Mice Confer Antidepressant-Like Effects to Naive Mice
Rebecca A. Brachman, Michael L. Lehmann, Dragan Maric, Miles Herkenham
Journal of Neuroscience 28 January 2015, 35 (4) 1530-1538; DOI: 10.1523/JNEUROSCI.2278-14.2015

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Lymphocytes from Chronically Stressed Mice Confer Antidepressant-Like Effects to Naive Mice
Rebecca A. Brachman, Michael L. Lehmann, Dragan Maric, Miles Herkenham
Journal of Neuroscience 28 January 2015, 35 (4) 1530-1538; DOI: 10.1523/JNEUROSCI.2278-14.2015
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Keywords

  • adaptive immune system
  • cytokines
  • depression
  • hippocampal neurogenesis
  • lymphocytes
  • stress

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