Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
    • Special Collections
  • EDITORIAL BOARD
    • Editorial Board
    • ECR Advisory Board
    • Journal Staff
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
    • Accessibility
  • SUBSCRIBE

User menu

  • Log out
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Neuroscience
  • Log out
  • Log in
  • My Cart
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
    • Special Collections
  • EDITORIAL BOARD
    • Editorial Board
    • ECR Advisory Board
    • Journal Staff
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
    • Accessibility
  • SUBSCRIBE
PreviousNext
Articles, Development/Plasticity/Repair

REST Regulates Non–Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II

Hyung Joon Kim, Ahmet M. Denli, Rebecca Wright, Tithi D. Baul, Gregory D. Clemenson, Ari S. Morcos, Chunmei Zhao, Simon T. Schafer, Fred H. Gage and Mohamedi N. Kagalwala
Journal of Neuroscience 4 November 2015, 35 (44) 14872-14884; https://doi.org/10.1523/JNEUROSCI.4286-14.2015
Hyung Joon Kim
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Hyung Joon Kim
Ahmet M. Denli
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rebecca Wright
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tithi D. Baul
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gregory D. Clemenson
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ari S. Morcos
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
2Program in Neuroscience, Harvard University, Boston, Massachusetts 02138
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chunmei Zhao
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Simon T. Schafer
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fred H. Gage
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Fred H. Gage
Mohamedi N. Kagalwala
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.4286-14.2015
PubMed 
26538656
Published By 
Society for Neuroscience
History 
  • Received October 16, 2014
  • Revision received September 28, 2015
  • Accepted October 6, 2015
  • First published November 4, 2015.
  • Version of record published November 4, 2015.
Copyright & Usage 
Copyright © 2015 the authors 0270-6474/15/3514872-13$15.00/0

Author Information

  1. Hyung Joon Kim1,*,
  2. Ahmet M. Denli1,*,
  3. Rebecca Wright1,
  4. Tithi D. Baul1,
  5. Gregory D. Clemenson1,
  6. Ari S. Morcos1,2,
  7. Chunmei Zhao1,
  8. Simon T. Schafer1,
  9. Fred H. Gage1, and
  10. Mohamedi N. Kagalwala1
  1. 1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, and
  2. 2Program in Neuroscience, Harvard University, Boston, Massachusetts 02138
  • G. D. Clemenson's present address: Center for the Neurobiology of Learning and Memory, University of California–Irvine, 320 Qureshey Research, Irvine, CA 92697.

  • C. Zhao's present address: Halozyme Therapeutics Inc., 11388 Sorrento Valley Road, San Diego, CA 92121.

View Full Text

Author contributions

  1. Author contributions: H.J.K., A.M.D., R.W., T.D.B., F.H.G., and M.N.K. designed research; H.J.K., A.M.D., R.W., T.D.B., G.D.C., A.S.M., C.Z., S.T.S., and M.N.K. performed research; H.J.K., A.M.D., R.W., T.D.B., A.S.M., and M.N.K. analyzed data; H.J.K., A.M.D., R.W., T.D.B., F.H.G., and M.N.K. wrote the paper.

  2. ↵*H.J.K. and A.M.D. contributed equally to this work.

  • G. D. Clemenson's present address: Center for the Neurobiology of Learning and Memory, University of California–Irvine, 320 Qureshey Research, Irvine, CA 92697.

  • C. Zhao's present address: Halozyme Therapeutics Inc., 11388 Sorrento Valley Road, San Diego, CA 92121.

Disclosures

    • Received October 16, 2014.
    • Revision received September 28, 2015.
    • Accepted October 6, 2015.
  • This work was supported by National Institutes of Health RO1 Grant NS050217 and R01 MH090258, the Leona M. and Harry B. Helmsley Charitable Trust grant #2012-PG-MED00, a California Institute for Regenerative Medicine Training Grant, the G. Harold and Leila Y. Mathers Charitable Foundation, the JPB Foundation, and the McDonnell Foundation. We thank Eunice Mejia, Nada B. Abdallah, Star W. Lee, Anthony Vu, Stefan Aigner, Iryna Gallina, and Galit Benoni for technical assistance and sharing materials; and Mary Lynn Gage for editorial comments.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to either of the following: Dr. Fred H. Gage, Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, gage{at}salk.edu; or Dr. Mohamedi N. Kagalwala, Neurogeneration Inc., 3210 Merryfield Row, San Diego, CA 92121, mnkagalwala{at}gmail.com

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2025-07-15
to
E.g., 2025-07-15

Article usage: January 2018 to July 2025

AbstractFullPdf
Jan 201812197
Feb 201810177
Mar 2018162810
Apr 201818287
May 20184224
Jun 2018114811
Jul 20189184
Aug 20186126
Sep 20184205
Oct 20188167
Nov 20185125
Dec 201851210
Total 201810825283
Jan 201993010
Feb 20198279
Mar 20196274
Apr 20199248
May 2019112211
Jun 20198207
Jul 201913276
Aug 20197149
Oct 201916156
Nov 201992126
Dec 20198177
Total 2019104244103
Jan 202073319
Feb 202013259
Mar 20206134
May 2020102810
Jun 202041415
Jul 202042414
Aug 20204136
Sep 20204168
Oct 2020153025
Nov 20205186
Dec 202072811
Total 202079242127
Jan 202182111
Feb 20214207
Mar 2021112711
Apr 202153413
May 20218167
Jun 20219214
Jul 202151210
Aug 202113410
Sep 202143215
Oct 202162425
Nov 202161723
Dec 20215173
Total 202172275139
Jan 202252217
Feb 202231011
Mar 202232816
Apr 202251910
May 202252121
Jun 202262416
Jul 202241710
Aug 20224155
Sep 202251710
Oct 202241710
Nov 2022122
Dec 2022292
Total 202247201130
Jan 202332010
Feb 20233127
Mar 20234266
Apr 20239162
May 202372117
Jun 20233179
Jul 202321213
Aug 20234128
Sep 202391914
Oct 20237165
Nov 20231931919
Dec 202393311
Total 202379523121
Jan 202423112
Feb 2024181810
Mar 202483412
Apr 2024122519
May 20247208
Jun 202482618
Jul 202432316
Aug 202475415
Sep 2024326610
Oct 2024685014
Nov 2024193712
Dec 202417213
Total 2024185456159
Jan 202534114
Feb 2025126315
Mar 2025103818
Apr 2025132021
May 20258379
Jun 2025102211
Jul 20250122
Total 20255623390
Total7302426952
Back to top

In this issue

The Journal of Neuroscience: 35 (44)
Journal of Neuroscience
Vol. 35, Issue 44
4 Nov 2015
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Advertising (PDF)
  • Ed Board (PDF)
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
REST Regulates Non–Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
REST Regulates Non–Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II
Hyung Joon Kim, Ahmet M. Denli, Rebecca Wright, Tithi D. Baul, Gregory D. Clemenson, Ari S. Morcos, Chunmei Zhao, Simon T. Schafer, Fred H. Gage, Mohamedi N. Kagalwala
Journal of Neuroscience 4 November 2015, 35 (44) 14872-14884; DOI: 10.1523/JNEUROSCI.4286-14.2015

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
REST Regulates Non–Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II
Hyung Joon Kim, Ahmet M. Denli, Rebecca Wright, Tithi D. Baul, Gregory D. Clemenson, Ari S. Morcos, Chunmei Zhao, Simon T. Schafer, Fred H. Gage, Mohamedi N. Kagalwala
Journal of Neuroscience 4 November 2015, 35 (44) 14872-14884; DOI: 10.1523/JNEUROSCI.4286-14.2015
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • adult neurogenesis
  • microfludics
  • neurosecretory
  • Rest/Nrsf
  • SCG2
  • stem cells

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Articles

  • Memory Retrieval Has a Dynamic Influence on the Maintenance Mechanisms That Are Sensitive to ζ-Inhibitory Peptide (ZIP)
  • Neurophysiological Evidence for a Cortical Contribution to the Wakefulness-Related Drive to Breathe Explaining Hypocapnia-Resistant Ventilation in Humans
  • Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase
Show more Articles

Development/Plasticity/Repair

  • Developmental Changes in Brain Cellular Membrane and Energy Metabolism: A Multi-Occasion 31P Magnetic Resonance Spectroscopy Study
  • The Epigenetic Reader PHF23 Is Required for Embryonic Neurogenesis
  • Microglia Support Both the Singular Form of LTP Expressed by the Lateral Perforant Path and Episodic Memory
Show more Development/Plasticity/Repair
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Accessibility
(JNeurosci logo)
(SfN logo)

Copyright © 2025 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.