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Brief Communications

Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex

Shiyong Huang, Kristen Hokenson, Sabita Bandyopadhyay, Shelley J. Russek and Alfredo Kirkwood
Journal of Neuroscience 2 December 2015, 35 (48) 15916-15920; DOI: https://doi.org/10.1523/JNEUROSCI.1813-15.2015
Shiyong Huang
1The Mind/Brain Institute, Johns Hopkins University, Baltimore, Maryland 21218,
2Program in Neuroscience, Hussman Institute for Autism, Baltimore, Maryland 21201,
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Kristen Hokenson
3Department of Pharmacology and Experimental Therapeutics, Laboratory of Translational Epilepsy, and
4Program in Biomolecular Pharmacology and Biomedical Neuroscience, Boston University School of Medicine, Boston, Massachusetts 02118, and
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Sabita Bandyopadhyay
3Department of Pharmacology and Experimental Therapeutics, Laboratory of Translational Epilepsy, and
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Shelley J. Russek
3Department of Pharmacology and Experimental Therapeutics, Laboratory of Translational Epilepsy, and
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Alfredo Kirkwood
1The Mind/Brain Institute, Johns Hopkins University, Baltimore, Maryland 21218,
5Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland 21205
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1813-15.2015
PubMed 
26631472
Published By 
Society for Neuroscience
History 
  • Received May 8, 2015
  • Revision received October 23, 2015
  • Accepted October 29, 2015
  • First published December 2, 2015.
  • Version of record published December 2, 2015.
Copyright & Usage 
Copyright © 2015 the authors 0270-6474/15/3515916-05$15.00/0

Author Information

  1. Shiyong Huang1,2,
  2. Kristen Hokenson3,4,
  3. Sabita Bandyopadhyay3,
  4. Shelley J. Russek3, and
  5. Alfredo Kirkwood1,5
  1. 1The Mind/Brain Institute, Johns Hopkins University, Baltimore, Maryland 21218,
  2. 2Program in Neuroscience, Hussman Institute for Autism, Baltimore, Maryland 21201,
  3. 3Department of Pharmacology and Experimental Therapeutics, Laboratory of Translational Epilepsy, and
  4. 4Program in Biomolecular Pharmacology and Biomedical Neuroscience, Boston University School of Medicine, Boston, Massachusetts 02118, and
  5. 5Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland 21205
View Full Text

Author contributions

  1. Author contributions: S.J.R. and A.K. designed research; S.H., K.H., and S.B. performed research; S.H., K.H., S.B., S.J.R., and A.K. analyzed data; S.J.R. and A.K. wrote the paper.

Disclosures

    • Received May 8, 2015.
    • Revision received October 23, 2015.
    • Accepted October 29, 2015.
  • This work was supported by the National Institutes of Health (Grant R05-EY12124 to A.K. and Grant NS4236301 to S.J.R.). We thank H.-K. Lee for valuable discussions and comments.

  • Correspondence should be addressed to Alfredo Kirkwood, Mind Brain Institute, Johns Hopkins University, 338 Krieger Hall, 3400 N. Charles St., Baltimore, MD 21218. kirkwood{at}jhu.edu

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Jan 201811104
Feb 20186123
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May 201817306
Jun 20187217
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Feb 20199115
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Total 20209313878
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Feb 2021121517
Mar 20218158
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Jul 20231139
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Total 20233819057
Total4291042520
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The Journal of Neuroscience: 35 (48)
Journal of Neuroscience
Vol. 35, Issue 48
2 Dec 2015
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Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex
Shiyong Huang, Kristen Hokenson, Sabita Bandyopadhyay, Shelley J. Russek, Alfredo Kirkwood
Journal of Neuroscience 2 December 2015, 35 (48) 15916-15920; DOI: 10.1523/JNEUROSCI.1813-15.2015

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Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex
Shiyong Huang, Kristen Hokenson, Sabita Bandyopadhyay, Shelley J. Russek, Alfredo Kirkwood
Journal of Neuroscience 2 December 2015, 35 (48) 15916-15920; DOI: 10.1523/JNEUROSCI.1813-15.2015
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Keywords

  • extrasynaptic receptors
  • δ-GABAA receptor
  • layer 2/3
  • pyramidal cells

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