Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE

User menu

  • Log in
  • My Cart

Search

  • Advanced search
Journal of Neuroscience
  • Log in
  • My Cart
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE
PreviousNext
Articles, Behavioral/Cognitive

Neuroimaging Evidence of a Bilateral Representation for Visually Presented Numbers

Mareike Grotheer, Karl-Heinz Herrmann and Gyula Kovács
Journal of Neuroscience 6 January 2016, 36 (1) 88-97; DOI: https://doi.org/10.1523/JNEUROSCI.2129-15.2016
Mareike Grotheer
1Institute of Psychology, Friedrich Schiller University Jena, 07737 Jena, Germany,
2Deutsche Forschungsgemeinschaft Research Unit Person Perception, Friedrich Schiller University Jena, 07743 Jena, Germany, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Karl-Heinz Herrmann
3Medical Physics Group, Institute for Diagnostic and Interventional Radiology, Jena University Hospital, 07743 Jena, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gyula Kovács
1Institute of Psychology, Friedrich Schiller University Jena, 07737 Jena, Germany,
2Deutsche Forschungsgemeinschaft Research Unit Person Perception, Friedrich Schiller University Jena, 07743 Jena, Germany, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Figures & Data

Figures

  • Figure 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 1.

    Stimuli used in Experiment 1. N, L, O, FN, FL, NN, and NL were presented.

  • Figure 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 2.

    Group analysis in Experiment 1. Significant activations were found in the right and left inferior temporal gyri when numbers were contrasted with false numbers and with all other presented stimuli. Further, we found significant activations in the left fusiform gyrus when letters were contrasted with false letters and all other presented stimuli. p < 0.05(FWE), cluster extend = 20 voxels.

  • Figure 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 3.

    ROI analysis in Experiment 1. A, Examples of the individual subjects' number-selective responses in the left and the right hemisphere. Results are based on the first run (contrasting numbers with all other stimuli, p < 0.001(uncorrected)) and presented on the respective individual brain anatomy. B, All of the individual participants' NFA (blue) and LFA (red) clusters superimposed on each other. Purple marks the overlap of the two areas. Images were created using MRIcroGL (http://www.mccauslandcenter.sc.edu/mricrogl/). C, Comparison of the activations (p < 0.005(uncorrected)) induced when contrasting numbers with all other stimuli between the three experimental runs (first run in blue, second run in yellow, third run in green, overlap in intermediate colors). D, ROI results. The right and left NFA respond stronger to numbers than to all other characters; conversely, the left LFA responds stronger to letters than to all other stimuli. RH, right hemisphere; LH, left hemisphere. *p < 0.05; **p < 0.01; ***p < 0.001 (Fisher LSD).

  • Figure 4.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 4.

    ROI analysis in Experiment 2. The right and left NFA respond stronger to single-digit numbers than to false numbers and letters. *p < 0.05; **p < 0.01; ***p < 0.001 (Fisher LSD).

  • Figure 5.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 5.

    A, Visualization of the impact of spatial resolution, localized shimming, and smoothing on the global mean BOLD signal intensity and tSNR. The mean BOLD response is increased in the neighborhood of the NFA (approximate NFA location is marked by black circles) by the higher spatial resolution. The tSNR is generally higher with the lower resolution; however, this effect is not as severe near the NFA. Smoothing increases the tSNR, particularly in the high-resolution images, so that, after preprocessing the tSNR near the NFA is largest in the high-resolution images. Images were created using Caret (Van Essen et al., 2001). B, Example of the position of the recorded volume (yellow box) and of the area where the localized shimming was performed (green box).

  • Figure 6.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 6.

    Influence of spatial resolution, localized shimming, and smoothing on the mean BOLD signal intensity (A) and tSNR (B) within the NFA. The mean BOLD signal is largest in the high-resolution images. Before smoothing, the tSNR is similar in the high-resolution and the lower-resolution images with and without localized shimming. After spatial smoothing was applied, the tSNR is largest in the high-resolution images. LR, lower resolution (3*3*3 mm3); LRS, lower resolution with localized shimming; HRS, high resolution (1*1*1 mm3) with localized shimming. *p < 0.05; **p < 0.01; ***p < 0.001 (Fisher LSD).

Back to top

In this issue

The Journal of Neuroscience: 36 (1)
Journal of Neuroscience
Vol. 36, Issue 1
6 Jan 2016
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Advertising (PDF)
  • Ed Board (PDF)
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Neuroimaging Evidence of a Bilateral Representation for Visually Presented Numbers
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Neuroimaging Evidence of a Bilateral Representation for Visually Presented Numbers
Mareike Grotheer, Karl-Heinz Herrmann, Gyula Kovács
Journal of Neuroscience 6 January 2016, 36 (1) 88-97; DOI: 10.1523/JNEUROSCI.2129-15.2016

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
Neuroimaging Evidence of a Bilateral Representation for Visually Presented Numbers
Mareike Grotheer, Karl-Heinz Herrmann, Gyula Kovács
Journal of Neuroscience 6 January 2016, 36 (1) 88-97; DOI: 10.1523/JNEUROSCI.2129-15.2016
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • high-resolution fMRI
  • inferior temporal gyrus
  • letter
  • number
  • signal-to-noise ratio
  • vision

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Articles

  • Choice Behavior Guided by Learned, But Not Innate, Taste Aversion Recruits the Orbitofrontal Cortex
  • Maturation of Spontaneous Firing Properties after Hearing Onset in Rat Auditory Nerve Fibers: Spontaneous Rates, Refractoriness, and Interfiber Correlations
  • Insulin Treatment Prevents Neuroinflammation and Neuronal Injury with Restored Neurobehavioral Function in Models of HIV/AIDS Neurodegeneration
Show more Articles

Behavioral/Cognitive

  • Cortically-evoked movement in humans reflects history of prior executions, not plan for upcoming movement
  • Anticipation of Appetitive Operant Action Induces Sustained Dopamine Release in the Nucleus Accumbens
  • Neither Enhanced Nor Lost: The Unique Role of Attention in Children's Neural Representations
Show more Behavioral/Cognitive
  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
(JNeurosci logo)
(SfN logo)

Copyright © 2023 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.