Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
    • Special Collections
  • EDITORIAL BOARD
    • Editorial Board
    • ECR Advisory Board
    • Journal Staff
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
    • Accessibility
  • SUBSCRIBE

User menu

  • Log out
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Neuroscience
  • Log out
  • Log in
  • My Cart
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
    • Special Collections
  • EDITORIAL BOARD
    • Editorial Board
    • ECR Advisory Board
    • Journal Staff
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
    • Accessibility
  • SUBSCRIBE
PreviousNext
Articles, Neurobiology of Disease

Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease

Jacqueline A. Bayliss, Moyra B. Lemus, Romana Stark, Vanessa V. Santos, Aiysha Thompson, Daniel J. Rees, Sandra Galic, John D. Elsworth, Bruce E. Kemp, Jeffrey S. Davies and Zane B. Andrews
Journal of Neuroscience 9 March 2016, 36 (10) 3049-3063; https://doi.org/10.1523/JNEUROSCI.4373-15.2016
Jacqueline A. Bayliss
1Department of Physiology, School of Biomedical and Psychological Sciences, Monash University, Clayton, Melbourne, Victoria 3800, Australia,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Moyra B. Lemus
1Department of Physiology, School of Biomedical and Psychological Sciences, Monash University, Clayton, Melbourne, Victoria 3800, Australia,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Romana Stark
1Department of Physiology, School of Biomedical and Psychological Sciences, Monash University, Clayton, Melbourne, Victoria 3800, Australia,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vanessa V. Santos
1Department of Physiology, School of Biomedical and Psychological Sciences, Monash University, Clayton, Melbourne, Victoria 3800, Australia,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Aiysha Thompson
2Molecular Neurobiology, Institute of Life Science, Swansea University, Swansea SA28PP, United Kingdom,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Daniel J. Rees
2Molecular Neurobiology, Institute of Life Science, Swansea University, Swansea SA28PP, United Kingdom,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sandra Galic
3St Vincent's Institute and Department of Medicine, The University of Melbourne, Fitzroy, Victoria 3065, Australia, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
John D. Elsworth
4Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06520
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bruce E. Kemp
3St Vincent's Institute and Department of Medicine, The University of Melbourne, Fitzroy, Victoria 3065, Australia, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jeffrey S. Davies
2Molecular Neurobiology, Institute of Life Science, Swansea University, Swansea SA28PP, United Kingdom,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jeffrey S. Davies
Zane B. Andrews
1Department of Physiology, School of Biomedical and Psychological Sciences, Monash University, Clayton, Melbourne, Victoria 3800, Australia,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Zane B. Andrews
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.4373-15.2016
PubMed 
26961958
Published By 
Society for Neuroscience
History 
  • Received December 6, 2015
  • Revision received January 21, 2016
  • Accepted January 30, 2016
  • First published March 9, 2016.
  • Version of record published March 9, 2016.
Copyright & Usage 
Copyright © 2016 the authors 0270-6474/16/363049-15$15.00/0

Author Information

  1. Jacqueline A. Bayliss1,
  2. Moyra B. Lemus1,
  3. Romana Stark1,
  4. Vanessa V. Santos1,
  5. Aiysha Thompson2,
  6. Daniel J. Rees2,
  7. Sandra Galic3,
  8. John D. Elsworth4,
  9. Bruce E. Kemp3,
  10. Jeffrey S. Davies2, and
  11. Zane B. Andrews1
  1. 1Department of Physiology, School of Biomedical and Psychological Sciences, Monash University, Clayton, Melbourne, Victoria 3800, Australia,
  2. 2Molecular Neurobiology, Institute of Life Science, Swansea University, Swansea SA28PP, United Kingdom,
  3. 3St Vincent's Institute and Department of Medicine, The University of Melbourne, Fitzroy, Victoria 3065, Australia, and
  4. 4Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06520
View Full Text

Author contributions

  1. Author contributions: J.A.B., A.T., B.E.K., J.S.D., and Z.B.A. designed research; J.A.B., R.S., M.B.L., V.V.S., A.T., D.J.R., S.G., J.D.E., B.E.K., and J.S.D. performed research; J.A.B., B.E.K., and Z.B.A. contributed unpublished reagents/analytic tools; J.A.B., R.S., J.D.E., B.E.K., J.S.D., and Z.B.A. analyzed data; J.A.B., J.S.D., and Z.B.A. wrote the paper.

Disclosures

    • Received December 6, 2015.
    • Revision received January 21, 2016.
    • Accepted January 30, 2016.
  • This work was supported by grants and fellowships from the Australian National Health and Medical Research Council to Z.B.A. (546131, 1084344) and B.E.K.; the Australian Research Council to Z.B.A. (FT100100966); and NIH NS056181 to J.H; and supported in part by the Victorian Government's Operational Infrastructure Support Program (B.E.K.), a St David's Medical Foundation Seed-Corn Grant (J.S.D.) and a Monash University Fellowship to Z.B.A.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr Zane B. Andrews, Monash University, Building 13F, Wellington Road, Clayton, Melbourne, Victoria 3800, Australia. Zane.Andrews{at}monash.edu

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2025-07-18
to
E.g., 2025-07-18

Article usage: January 2018 to July 2025

AbstractFullPdf
Jan 20189011112
Feb 20185914823
Mar 2018248829
Apr 20189385613
May 2018136815
Jun 2018194317
Jul 2018105912
Aug 201873013
Sep 2018165711
Oct 2018125911
Nov 2018810019
Dec 2018146524
Total 20181210884199
Jan 2019178623
Feb 2019298325
Mar 2019456652
Apr 20191275224
May 2019546026
Jun 2019154324
Jul 201993619
Aug 2019144016
Oct 2019465620
Nov 2019653123
Dec 2019236518
Total 2019444618270
Jan 2020154517
Feb 2020144717
Mar 2020255731
May 2020115046
Jun 2020142613
Jul 2020114422
Aug 202093316
Sep 2020185531
Oct 2020203818
Nov 2020205734
Dec 2020194619
Total 2020176498264
Jan 202199524
Feb 202193826
Mar 202195025
Apr 202174620
May 202133936
Jun 2021114219
Jul 20217367
Aug 2021173524
Sep 2021113519
Oct 202175128
Nov 2021136226
Dec 2021215424
Total 2021124583278
Jan 2022236736
Feb 202265033
Mar 2022125438
Apr 2022116619
May 202294442
Jun 202232816
Jul 202272910
Aug 2022213911
Sep 202275215
Oct 2022125821
Nov 20227126
Dec 20225234
Total 2022123522251
Jan 2023125118
Feb 202318419
Mar 2023153426
Apr 2023113718
May 2023181914
Jun 202310499
Jul 2023174827
Aug 2023164815
Sep 202336317
Oct 2023133911
Nov 2023137618
Dec 2023197715
Total 2023165582197
Jan 2024317362
Feb 202444122
Mar 202495124
Apr 20241037525
May 2024136820
Jun 20241489
Jul 202473512
Aug 202452516
Sep 202464713
Oct 2024177022
Nov 202476618
Dec 20244837
Total 2024114982250
Jan 2025185519
Feb 2025189615
Mar 202575726
Apr 202565313
May 20258669
Jun 202564317
Jul 202552110
Total 202568391109
Total242450601818
Back to top

In this issue

The Journal of Neuroscience: 36 (10)
Journal of Neuroscience
Vol. 36, Issue 10
9 Mar 2016
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Advertising (PDF)
  • Ed Board (PDF)
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease
Jacqueline A. Bayliss, Moyra B. Lemus, Romana Stark, Vanessa V. Santos, Aiysha Thompson, Daniel J. Rees, Sandra Galic, John D. Elsworth, Bruce E. Kemp, Jeffrey S. Davies, Zane B. Andrews
Journal of Neuroscience 9 March 2016, 36 (10) 3049-3063; DOI: 10.1523/JNEUROSCI.4373-15.2016

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease
Jacqueline A. Bayliss, Moyra B. Lemus, Romana Stark, Vanessa V. Santos, Aiysha Thompson, Daniel J. Rees, Sandra Galic, John D. Elsworth, Bruce E. Kemp, Jeffrey S. Davies, Zane B. Andrews
Journal of Neuroscience 9 March 2016, 36 (10) 3049-3063; DOI: 10.1523/JNEUROSCI.4373-15.2016
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • AMPK
  • calorie restriction
  • ghrelin
  • stereology
  • substantia nigra

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Articles

  • Memory Retrieval Has a Dynamic Influence on the Maintenance Mechanisms That Are Sensitive to ζ-Inhibitory Peptide (ZIP)
  • Neurophysiological Evidence for a Cortical Contribution to the Wakefulness-Related Drive to Breathe Explaining Hypocapnia-Resistant Ventilation in Humans
  • Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase
Show more Articles

Neurobiology of Disease

  • Multi-omics analysis reveals miR-7220-5p alleviates N2O addictive behaviors via NR2B/ERK/CREB signaling
  • Disrupted Neurogenesis from Basal Intermediate Precursor Cells Alters the Postnatal Neocortex in the TcMAC21 Mouse model of Down Syndrome
  • Positron Emission Tomography (PET) Neuroimaging of the Pink1-/- Rat Parkinson Disease Model with the Norepinephrine Transporter (NET) Ligand [18F]NS12137
Show more Neurobiology of Disease
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Accessibility
(JNeurosci logo)
(SfN logo)

Copyright © 2025 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.