Article Information
- Received October 28, 2015
- Revision received January 30, 2016
- Accepted February 15, 2016
- First published March 30, 2016.
- Version of record published March 30, 2016.
Author Information
- Theresa E. Bjorness1,2,
- Nicholas Dale3,
- Gabriel Mettlach1,
- Alex Sonneborn1,
- Bogachan Sahin4,
- Allen A. Fienberg5,
- Masashi Yanagisawa6,7,
- James A. Bibb1,8, and
- Robert W. Greene1,2,7,9
- 1Department of Psychiatry, University of Texas Southwestern, Dallas, Texas 75390,
- 2Veterans Administration Medical Center, Dallas, Texas 75216,
- 3Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom,
- 4Department of Neurology, University of Rochester, Rochester, New York 14642,
- 5Intra-Cellular Therapies, New York, New York 10032,
- 6Department of Molecular Genetics, University of Texas Southwestern, Dallas, Texas 75390,
- 7International Institute for Integrative Sleep Medicine, University of Tsukuba, Tsukuba, Japan 305-8577,
- 8Department of Neurology and Neurotherapeutics, University of Texas Southwestern, Dallas, Texas 75390, and
- 9Department of Neuroscience, University of Texas Southwestern, Dallas, Texas 75390
Author contributions
Author contributions: T.E.B., J.A.B., and R.W.G. designed research; T.E.B., N.D., G.M., A.S., and R.W.G. performed research; N.D., A.A.F., B.S., and J.A.B. contributed unpublished reagents/analytic tools; T.E.B., N.D., G.M., A.S., M.Y., and R.W.G. analyzed data; T.E.B., M.Y., and R.W.G. wrote the paper.
Disclosures
- Received October 28, 2015.
- Revision received January 30, 2016.
- Accepted February 15, 2016.
This work was supported by the National Institutes of Health Grants MH 06777 and NS075545, the Department of Veterans Affairs, Dallas Veterans Administration Medical Center Grants MH79710, MH083711, and DA016672 to R.W.G. and to J.A.B., a sponsored agreement between University of Texas Southwestern Medical Center to J.A.B., A.A.F., and R.W.G., Intra-Cellular Therapies, Inc., and the Japan Society for the Promotion of Science through the Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST) to M.Y. We thank Dr. Frank Kirchhoff for the generous gift of GFAP:CreER mice; Dr. Amelia Eisch for help with the tamoxifen injection protocol; Dr. Detlev Boison for help with preliminary Western analysis of AdK knockdown; Dr. Ayako Suzuki for the qPCR analysis of AdK expression; and Lehong Nguyen for technical assistance.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Robert W. Greene, 5323 Harry Hines Blvd, Dallas, TX 75390-9070. E-mail: robertw.greene{at}utsouthwestern.edu
