Article Information
- Received April 29, 2015
- Revision received November 18, 2015
- Accepted November 30, 2015
- First published January 20, 2016.
- Version of record published January 20, 2016.
Author Information
- Margaret H. Magdesian1,2,*,
- G. Monserratt Lopez-Ayon1,*,
- Megumi Mori1,
- Dominic Boudreau3,4,
- Alexis Goulet-Hanssens5,
- Ricardo Sanz2,
- Yoichi Miyahara1,
- Christopher J. Barrett3,4,
- Alyson E. Fournier2,
- Yves De Koninck3,4,6, and
- Peter Grütter1
- 1Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada,
- 2Department of Neurology and Neurosurgery, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada,
- 3Institut Universitaire en Santé Mentale de Québec, Quebec, Quebec G1J 2G3, Canada,
- 4Department of Psychiatry and Neuroscience, Université Laval, Quebec, Quebec G1V 0A6, Canada,
- 5Department of Chemistry, McGill University, Montreal, Quebec H3A 2K6, Canada, and
- 6Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec H3A 1Y6, Canada
Author contributions
Author contributions: M.H.M., G.M.L.-A., C.J.B., A.E.F., Y.D.K., and P.G. designed research; M.H.M., G.M.L.-A., M.M., D.B., A.G.-H., R.S., and Y.M. performed research; M.H.M. and P.G. contributed unpublished reagents/analytic tools; M.H.M., G.M.L.-A., Y.D.K., and P.G. analyzed data; M.H.M., G.M.L.-A., and P.G. wrote the paper.
↵*M.H.M. and G.M.L.-A. contributed equally to this work.
Disclosures
- Received April 29, 2015.
- Revision received November 18, 2015.
- Accepted November 30, 2015.
This work was supported by the following (to P.G.): Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery Grant, McGill University, James McGill research stipend, Le regroupement québécois sur les matériaux de pointe—Fond de recherche du Québec—Nature et technologies, Canadian Institutes of Health Research Training Grant, and NSERC Collaborative Research and Training Experience. We thank Dr. Edward Ruthazer and Dr. Delphine Gobert for critical discussions, contributions to experimental design, and elaboration of the manuscript; Dr. David Oliver for contributions on experimental design, data analysis, and elaboration of the manuscript; Dr. William Paul for technical support with electrophysiology setup; Jean-François Desjardins for data analysis discussions; Xue Ying Chua for help with cell cultures; Dr. Celia Greenwood for valuable discussions on data analysis and statistics; Dr. Paul De Koninck for helpful discussions on experimental design; Dr. Tim E. Kennedy and Stephen Glasgow for helpful discussions; and Robert Gagnon and John Smeros for technical support.
The authors declare a potential conflict of interest. The devices and methods presented in this manuscript are protected by patent applications.
- Correspondence should be addressed to Professor Peter Grütter, Chair and James McGill Professor, Department of Physics, McGill University, 3600 University Street, Rm 108, Montreal, QC H3A 2T8, Canada. peter.grutter{at}mcgill.ca