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Articles, Behavioral/Cognitive

Medial Orbitofrontal Neurons Preferentially Signal Cues Predicting Changes in Reward during Unblocking

Nina Lopatina, Michael A. McDannald, Clay V. Styer, Jacob F. Peterson, Brian F. Sadacca, Joseph F. Cheer and Geoffrey Schoenbaum
Journal of Neuroscience 10 August 2016, 36 (32) 8416-8424; DOI: https://doi.org/10.1523/JNEUROSCI.1101-16.2016
Nina Lopatina
1National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224,
3University of Maryland School of Medicine, Program in Neuroscience, Baltimore, Maryland 21201,
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Michael A. McDannald
2Department of Psychology, Boston College, Chestnut Hill, Massachusetts 02467,
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Clay V. Styer
1National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224,
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Jacob F. Peterson
1National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224,
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Brian F. Sadacca
1National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224,
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Joseph F. Cheer
4University of Maryland School of Medicine, Department of Anatomy and Neurobiology, Baltimore, Maryland 21201, and
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Geoffrey Schoenbaum
1National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224,
4University of Maryland School of Medicine, Department of Anatomy and Neurobiology, Baltimore, Maryland 21201, and
5Johns Hopkins University, Department of Neuroscience, Baltimore, Maryland 21205
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1101-16.2016
PubMed 
27511013
Published By 
Society for Neuroscience
History 
  • Received April 1, 2016
  • Revision received May 28, 2016
  • Accepted June 21, 2016
  • First published August 10, 2016.
  • Version of record published August 10, 2016.
Copyright & Usage 
Copyright © 2016 the authors 0270-6474/16/368416-09$15.00/0

Author Information

  1. Nina Lopatina1,3,
  2. Michael A. McDannald2,
  3. Clay V. Styer1,
  4. Jacob F. Peterson1,
  5. Brian F. Sadacca1,
  6. Joseph F. Cheer4, and
  7. Geoffrey Schoenbaum1,4,5
  1. 1National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224,
  2. 2Department of Psychology, Boston College, Chestnut Hill, Massachusetts 02467,
  3. 3University of Maryland School of Medicine, Program in Neuroscience, Baltimore, Maryland 21201,
  4. 4University of Maryland School of Medicine, Department of Anatomy and Neurobiology, Baltimore, Maryland 21201, and
  5. 5Johns Hopkins University, Department of Neuroscience, Baltimore, Maryland 21205
View Full Text

Author contributions

  1. Author contributions: N.L., M.A.M., B.F.S., J.F.C., and G.S. designed research; N.L., C.V.S., J.F.P., and B.F.S. performed research; N.L. analyzed data; N.L., M.A.M., B.F.S., J.F.C., and G.S. wrote the paper.

Disclosures

    • Received April 1, 2016.
    • Revision received May 28, 2016.
    • Accepted June 21, 2016.
  • This work was supported by the Intramural Research Program at the National Institute on Drug Abuse. The opinions expressed in this article are the authors' own and do not reflect the view of the National Institutes of Health/Department of Health and Human Services.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Geoffrey Schoenbaum, Cellular Neurobiology Research Branch, Behavioral Neurophysiology Research Section, 251 Bayview Blvd, Suite 200, Bldg BRC, Room 06A705, Baltimore, MD 21224. geoffrey.schoenbaum{at}nih.gov

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In this issue

The Journal of Neuroscience: 36 (32)
Journal of Neuroscience
Vol. 36, Issue 32
10 Aug 2016
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Medial Orbitofrontal Neurons Preferentially Signal Cues Predicting Changes in Reward during Unblocking
Nina Lopatina, Michael A. McDannald, Clay V. Styer, Jacob F. Peterson, Brian F. Sadacca, Joseph F. Cheer, Geoffrey Schoenbaum
Journal of Neuroscience 10 August 2016, 36 (32) 8416-8424; DOI: 10.1523/JNEUROSCI.1101-16.2016

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Medial Orbitofrontal Neurons Preferentially Signal Cues Predicting Changes in Reward during Unblocking
Nina Lopatina, Michael A. McDannald, Clay V. Styer, Jacob F. Peterson, Brian F. Sadacca, Joseph F. Cheer, Geoffrey Schoenbaum
Journal of Neuroscience 10 August 2016, 36 (32) 8416-8424; DOI: 10.1523/JNEUROSCI.1101-16.2016
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Keywords

  • orbitofrontal
  • Pavlovian
  • rat
  • single unit

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