Article Information
- Received December 2, 2015
- Revision received August 21, 2016
- Accepted August 23, 2016
- First published October 5, 2016.
- Version of record published October 5, 2016.
Author Information
- Jack DiGiovanna1,*,
- Nadia Dominici2,3,*,
- Lucia Friedli2,
- Jacopo Rigosa1,4,
- Simone Duis2,
- Julie Kreider2,
- Janine Beauparlant2,
- Rubia van den Brand2,
- Marco Schieppati5,
- Silvestro Micera1,4,†, and
- Grégoire Courtine2,†
- 1Bertarelli Foundation Chair in Translational Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne 1005, Switzerland,
- 2International Paraplegic Foundation Chair Spinal Cord Repair, Center for Neuroprosthetics and Brain Mind Institute, Swiss Federal Institute of Technology (EPFL), Lausanne 1015, Switzerland,
- 3MOVE Research Institute Amsterdam, Department of Human Movement Sciences, VU University Amsterdam, Amsterdam 1081 HV, The Netherlands,
- 4Translational Neural Engineering Area, The BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa 56127, Italy, and
- 5Department of Public Health, Experimental and Forensic Medicine, University of Pavia, and Fondazione Salvatore Maugeri (IRCCS), Centro Studi Attività Motorie (CSAM), Pavia 27100, Italy
Author contributions
Author contributions: J.D., M.S., S.M., and G.C. designed research; J.D., N.D., L.F., S.D., J.K., J.B., and R.v.d.B. performed research; J.D., N.D., J.R., and J.K. contributed unpublished reagents/analytic tools; J.D., N.D., J.R., J.B., and G.C. analyzed data; J.D., M.S., and G.C. wrote the paper.
↵*J.D. and N.D. contributed equally to this work.
↵†S.M. and G.C. contributed equally to this work.
Disclosures
- Received December 2, 2015.
- Revision received August 21, 2016.
- Accepted August 23, 2016.
This work was supported by European Research Council Starting Grant ERC 261247, Walk Again, European Community's Seventh Framework Program CP-IP 258654, NeuWALK, and the National Center of Competence in Research in Robotics. We thank Michelle Hürlimann for behavioral training and recording; Jean Laurens for helpful feedback on the manuscript; Alessandro Panarese for assistance with the preprocessing architecture for spike sorting; and Joachim von Zitzewitz for 3D rat rendering.
The authors declare no competing financial interests.
- Correspondence should be addressed to either of the following: Dr. Jack DiGiovanna, EPFL STI CNP TNE, BM 3114-5-6 (Bâtiment BM), Station 17, CH-1015 Lausanne, Switzerland. jack.digiovanna{at}gmail.com; or Dr. Grégoire Courtine, EPFL SV BMI UPCOURTINE, Office: AI 1240, Station 19, CH-1015 Lausanne, Switzerland. gregoire.courtine{at}epfl.ch
