Article Information
- Received September 15, 2015
- Revision received December 16, 2015
- Accepted January 15, 2016
- First published February 24, 2016.
- Version of record published February 24, 2016.
Author Information
- Ahmed S. Abdelfattah1,
- Samouil L. Farhi2,*,
- Yongxin Zhao1,*,
- Daan Brinks2,
- Peng Zou2,
- Araya Ruangkittisakul3,
- Jelena Platisa4,5,
- Vincent A. Pieribone4,5,6,
- Klaus Ballanyi3,
- Adam E. Cohen2,7,8, and
- Robert E. Campbell1
- 1Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada,
- 2Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138,
- 3Department of Physiology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada,
- 4The John B. Pierce Laboratory, Inc., New Haven, Connecticut 06519,
- 5Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520,
- 6Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06510,
- 7Department of Physics, Harvard University, Cambridge, Massachusetts 02138, and
- 8Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts 02138
Author contributions
Author contributions: V.A.P., K.B., A.E.C., and R.E.C. designed research; A.S.A., S.L.F., Y.Z., D.B., P.Z., A.R., and J.P. performed research; A.S.A., S.L.F., Y.Z., D.B., and P.Z. analyzed data; A.S.A., S.L.F., A.E.C., and R.E.C. wrote the paper.
↵*S.L.F. and Y.Z. contributed equally to this work.
Disclosures
- Received September 15, 2015.
- Revision received December 16, 2015.
- Accepted January 15, 2016.
This work was supported by grants from the Canada Foundation of Innovation/Alberta Advanced Education and Technology (K.B.), Alberta Innovates and Alberta Innovates Health Solutions (Scientist Award to K.B), Harvard Center for Brain Science (A.E.C.), PECASE (Award N00014-11-1-0549 to A.E.C.), the National Institutes of Health (Grants 1-R01-EB012498-01 and New Innovator Grant 1-DP2-OD007428 to A.E.C.), the Howard Hughes Medical Institute (A.E.C.), the Canadian Institutes of Health Research (Grant MOP-123514 to R.E.C.), and the Natural Sciences and Engineering Research Council of Canada (Grant RGPIN 288338-2010 to R.E.C.). A.S.A. was supported by a Vanier Canada Graduate Scholarship (NSERC), an Alberta Innovates Health Solutions Scholarship, and a University of Alberta Doctoral Distinction award. S.L.F. was supported by a National Science Foundation Graduate Research Fellowship. Y.Z. was supported by a University of Alberta Fellowship and an Alberta Innovates Scholarship. R.E.C. held a Tier II Canada Research Chair. We thank the University of Alberta's Molecular Biology Service Unit, the Department of Chemistry's Electronics Unit, and Christopher W. Cairo for technical support and assistance. The Orca Flash2.8 camera was a generous gift from Michael W. Davidson. Humanized-PsChR-eYFP under CMV control in pcDNA3.1 backbone was generously provided by J. Spudich. pGEMTEZ-Kir2.1 was a gift from Richard Axel, Joseph Gogos, and C. Ron Yu (Addgene plasmid #32641). The constructs described in this manuscript will be available on Addgene. A.E.C. is a founder of Q-State Biosciences. The remaining authors declare no competing financial interests.
- Correspondence should be addressed to Robert E. Campbell, Department of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, Alberta T6G 2G2, Canada. robert.e.campbell{at}ualberta.ca
