This image shows a neural rosette derived from a pluripotent stem cell. Apical localization of N-cadherin (red) is seen, with beta III tubulin (green) showing both polarized rosette cells, and non-polarized neuronal cells outside of the rosette. Nuclei are visualized with DAPI (blue). For more information, see the article by Coulthard, Hawksworth et al. (pages 5395–5407).