This image shows a male brain of Drosophila subobscura doubly stained by the Venus marker knocked into the fruitless locus (green) and the antibody against Fruitless (purple), a neural masculinizer protein. Optogenetic activation of this fruitless-labeled circuitry induces a series of species-specific courtship behavior, including actions for nuptial gift transfer. This study opens up an avenue for genetic studies on the neural basis of diversified behavior in non-model organisms. For more information see the article by Tanaka et al. (pages 11662–11674).