Article Information
- Received May 22, 2017
- Revision received January 23, 2018
- Accepted February 12, 2018
- First published February 26, 2018.
- Version of record published April 4, 2018.
Author Information
- Kijung Sung1,
- Luiz F. Ferrari3,
- Wanlin Yang1,4,
- ChiHye Chung5,
- Xiaobei Zhao1,
- Yingli Gu1,6,
- Suzhen Lin1,4,
- Kai Zhang7,9,
- Bianxiao Cui7,
- Matthew L. Pearn2,10,
- Michael T. Maloney8,
- William C. Mobley1,
- Jon D. Levine3, and
- Chengbiao Wu1,10
- 1Department of Neurosciences,
- 2Department of Anesthesiology, University of California San Diego, School of Medicine, La Jolla, California 92093,
- 3Department of Oral Surgery, University of California San Francisco, San Francisco, California 94143,
- 4Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China 200025,
- 5Department of Biological Sciences, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 143-701, South Korea,
- 6Department of Neurology, the Fourth Hospital of Harbin Medical University, Harbin, Heilongjiang, China 150001,
- 7Department of Chemistry,
- 8Department of Neurosciences, Stanford University, Stanford, California 94305,
- 9Department of Biochemistry, Neuroscience Program, Center for Biophysics and Quantitative Biology, Chemistry-Biology Interface Training Program, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, and
- 10V.A. San Diego Healthcare System, San Diego, California 92161
Author contributions
Author contributions: K.S., L.F.F., W.Y., X.Z., K.Z., B.C., W.C.M., J.D.L., and C.W. designed research; K.S., L.F.F., W.Y., C.C., X.Z., Y.G., S.L., K.Z., M.L.P., M.T.M., and C.W. performed research; K.S., W.Y., M.L.P., M.T.M., W.C.M., J.D.L., and C.W. analyzed data; K.S., W.C.M., J.D.L., and C.W. wrote the paper.
Disclosures
- Received May 22, 2017.
- Revision received January 23, 2018.
- Accepted February 12, 2018.
This work was supported by the National Institutes of Health [Grant PN2 EY016525 and University of California–San Diego (UCSD) Alzheimer's Disease Research Center P50 Pilot Grant to W.C.M.; Grant R01 NS084545 to J.D.L.; and UCSD T32 Neuroplasticity of Aging Training Grant to K.S.], the Down Syndrome Research and Treatment Foundation (W.C.M.), the Larry L. Hillblom Foundation (W.C.M.), the Alzheimer's Association (W.C.M., the Thrasher Research Fund (W.C.M.), and the Larry L. Hillblom Foundation (Tauopathy Foundation startup grant to C.W.). We thank Pauline Hu for assistance in DRG cultures, and R. Shibata and N.D. Storslett for assistance with protein purification.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Chengbiao Wu, Department of Neurosciences, University of California San Diego, Medical Teaching Facility, Room 312 MC-0624, 9500 Gilman Drive, La Jolla, CA 92093. chw049{at}ucsd.edu
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