Article Information
- Received November 18, 2017
- Revision received May 7, 2018
- Accepted May 11, 2018
- First published May 21, 2018.
- Version of record published June 13, 2018.
Author Information
Author contributions
Author contributions: Y.N., T.N., and I.T. designed research; Y.N., T.N., H.S., J.S., R.A., and S.M. performed research; Y.N., T.N., K.H., T.O., and Y.D. contributed unpublished reagents/analytic tools; Y.N., T.N., H.S., J.S., R.A., S.M., and I.T. analyzed data; Y.N., T.N., and I.T. wrote the paper.
Disclosures
- Received November 18, 2017.
- Revision received May 7, 2018.
- Accepted May 11, 2018.
This work was supported by Grants-in-Aid for Scientific Research (KAKENHI, 15H04755 and 15K15181) from the Japan Society for the Promotion of Science. We thank Richard Steele for careful reading of this manuscript. We thank Drs. Ken-ichi Hosoya and Shin-ichi Akanuma at the University of Toyama for constructive comments and technical advice and for providing antibodies to detect Oatp2a1. We also thank Dr. Eiichi Hinoi and Maika Okamoto for assistance with measuring colorectal temperature.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Takeo Nakanishi, Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan. nakanish{at}p.kanazawa-u.ac.jp
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