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Research Articles, Development/Plasticity/Repair

Muscarinic Receptor M3R Signaling Prevents Efficient Remyelination by Human and Mouse Oligodendrocyte Progenitor Cells

R. Ross Welliver, Jessie J. Polanco, Richard A. Seidman, Anjali K. Sinha, Melanie A. O'Bara, Zainab M. Khaku, Diara A. Santiago González, Akiko Nishiyama, Jurgen Wess, M. Laura Feltri, Pablo M. Paez and Fraser J. Sim
Journal of Neuroscience 1 August 2018, 38 (31) 6921-6932; https://doi.org/10.1523/JNEUROSCI.1862-17.2018
R. Ross Welliver
1Neuroscience Program,
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Jessie J. Polanco
1Neuroscience Program,
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Richard A. Seidman
1Neuroscience Program,
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Anjali K. Sinha
1Neuroscience Program,
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Melanie A. O'Bara
2Department of Pharmacology and Toxicology, and
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Zainab M. Khaku
2Department of Pharmacology and Toxicology, and
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Diara A. Santiago González
2Department of Pharmacology and Toxicology, and
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Akiko Nishiyama
4Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut 06269, and
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Jurgen Wess
5Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892
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M. Laura Feltri
1Neuroscience Program,
3Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, Center for Hearing and Deafness, University at Buffalo, Buffalo, New York 14214,
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Pablo M. Paez
1Neuroscience Program,
2Department of Pharmacology and Toxicology, and
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Fraser J. Sim
1Neuroscience Program,
2Department of Pharmacology and Toxicology, and
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The Journal of Neuroscience: 38 (31)
Journal of Neuroscience
Vol. 38, Issue 31
1 Aug 2018
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Muscarinic Receptor M3R Signaling Prevents Efficient Remyelination by Human and Mouse Oligodendrocyte Progenitor Cells
R. Ross Welliver, Jessie J. Polanco, Richard A. Seidman, Anjali K. Sinha, Melanie A. O'Bara, Zainab M. Khaku, Diara A. Santiago González, Akiko Nishiyama, Jurgen Wess, M. Laura Feltri, Pablo M. Paez, Fraser J. Sim
Journal of Neuroscience 1 August 2018, 38 (31) 6921-6932; DOI: 10.1523/JNEUROSCI.1862-17.2018

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Muscarinic Receptor M3R Signaling Prevents Efficient Remyelination by Human and Mouse Oligodendrocyte Progenitor Cells
R. Ross Welliver, Jessie J. Polanco, Richard A. Seidman, Anjali K. Sinha, Melanie A. O'Bara, Zainab M. Khaku, Diara A. Santiago González, Akiko Nishiyama, Jurgen Wess, M. Laura Feltri, Pablo M. Paez, Fraser J. Sim
Journal of Neuroscience 1 August 2018, 38 (31) 6921-6932; DOI: 10.1523/JNEUROSCI.1862-17.2018
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Keywords

  • CHRM3
  • demyelination
  • human
  • lentivirus
  • remyelination
  • transplantation

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