This image shows a dopaminergic neuron immunostained for cytosolic tyrosine hydroxylase (red), plasma-membrane-bound dopamine transporter (green), and nuclear DAPI staining (blue). The neuron was generated from BMP5/7-treated human induced pluripotent stem cells. The BMP/SMAD pathway has a critical role in the formation of dopaminergic neurons in vivo and from human stem cells. For more information see the article by Jovanovic and Salti et al. (pages 1662–1676).